“…Considering that receiving a cancer diagnosis is already associated with feeling powerless (Lin et al, 2020 ) and hopeless (Meggiolaro et al, 2016 ; Uslu-Sahan et al, 2019 ) due to the unexpected and unpredictable nature of the disease (Lin et al, 2020 ), psycho-oncological VR therapies should assist patients in recovering control over their life (McCarley, 2009 ) by empowering them. Through empowerment, people achieve mastery over their own life (Rappaport, 1987 ) and change (Brown et al, 2015 ; Buddelmeyer and Powdthavee, 2016 ), improving disease management, health status, medication adherence (Nafradi et al, 2017 ) and health outcomes (Marimuthu et al, 2022 ), thus becoming active participants in their treatment (Tsay and Hung, 2004 ). Being actively engaged reassures, indeed, patients that they can achieve control over their medical condition, contributing to their satisfaction, fulfillment, and well-being (Marimuthu et al, 2022 ).…”