Understanding the role of surface interactions in the antibacterial activity of layered double hydroxide nanoparticles by atomic force microscopy

Abstract

Understanding the mechanisms of interactions between zinc-based layered double hydroxides (LDHs) and bacterial surfaces becomes of great importance to improve the efficiency of these antibiotic-free antibacterial agents. In fact, the...

NAP-XPS Probes the Electronic Structure of the Mg–Al–Cl Layered Double Hydroxide upon Controlled Hydration

“…Especially, the NAP-XPS shed light on the mechanism involving LDH surface properties for pollutants sequestration 10,11 or antibacterial effect. 12 Chloride Oxidation. As already reported in previous studies 3,4,42 focusing on 6 M NaCl solution, two Cl 2p components of comparable intensities (in surface-sensitive conditions) were observed at 197.6 and 199.8 eV.…”

“…To the best of our knowledge, this is the first description of the external surface of LDH at high RH , and it may help the understanding of the behavior of this class of material under environmental conditions. Especially, the NAP-XPS shed light on the mechanism involving LDH surface properties for pollutants sequestration , or antibacterial effect …”

“…NAP-XPS offered new opportunities in the field of heterogeneous catalysis (gas/solid interface) , and also made it possible to probe gas/liquid interface (e.g., the study of solution surfaces began a decade ago). , Recently, the behavior of swelling clays whose layered structure allows the adsorption of a large amount of water was also examined . Among lamellar materials, double lamellar hydroxides (LDH) has been widely studied as fire retardant, catalyst, , drug releaser, pollutants adsorbant, , or antibacterial agent . LDH properties depend on their hydration state which is the subject of a thriving research field. ,, Nevertheless, as far as we know, their electronic structure in hydrated state has not already been examined by NAP-XPS, which is the point of this work.…”

“…5 Among lamellar materials, double lamellar hydroxides (LDH) has been widely studied as fire retardant, 6 catalyst, 7,8 drug releaser, 9 pollutants adsorbant, 10,11 or antibacterial agent. 12 LDH properties depend on their hydration state which is the subject of a thriving research field. 10,13,14 Nevertheless, as far as we know, their electronic structure in hydrated state has not already been examined by NAP-XPS, which is the point of this work.…”

pH-Responsive Inorganic/Organic Nanohybrids System for Controlled Nicotinic Acid Drug Release

“…The inorganic material is based on layered double hydroxide (LDH) due to its efficiency in controlling drug release at the molecular level in a sustained manner. LDH, anionic clay, has a positively charged hydroxide lattice, with the brucite structure and replaceable hydrated anions and H 2 O molecules in the interlayer [ 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 ]. The LDH drug delivery system has been attracting the scientific community owing to its ease of preparation, improved drug bioavailability, stability, better pharmacological performance with no toxicity and, most importantly, good controllability on drug release in a sustained fashion [ 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 ].…”