Unha cirúrgica de biopolímero de cana de açúcar para preservação do leito ungueal após avulsão

Pinto

Ferraz-Carvalho

et al. 2020

J Mater Sci: Mater Med

Avulsion of the nail plate is the most accomplished surgical procedure among the nail apparatus surgeries. Since it is not possible to use the removed nail to cover the nail bed, some materials have been suggested, however, they are generally not available for use and often at a high cost. To evaluate the use of Bacterial Cellulose (BC) dressing as a biological nail (Bio-Nail) after partial or total avulsion of the nail plate. Twenty-six candidates for nail avulsion, were randomized into two groups: Control, using Vaseline with gauze (11 patients) and Experimental group, BC group, using the Bio-Nail (15 patients). The patients were followed up during the 180-day period. The distribution of the patients in the groups was homogeneous for both sociodemographic and clinical data. The occurrence of infection (1 case in the control group) was not statistically relevant. The BC group had lower pain intensity (p = 0.011) with earlier temporal resolution when compared to the control group (p = 0.003). The BC group presented earlier reepithelization (p = 0.022) and better quantitative (p = 0.021) and qualitative conditions (p = 0.011) for the exudate. Regarding satisfaction, all the patients were satisfied. Good preservation of the nail plate area was observed in the BC group at the end of the 180-day period (p = 0.024). Average time of BC dressing permanence was 16.4 ± 7.1 days. BC showed to be appropriate as a dressing after partial or total avulsion of the nail plate. BC is a Bio-Nail promising for nail bed healing.

Section: Discussionmentioning

confidence: 99%

“…The Bio-Nail is a biological nail based on bacterial cellulose (BC) matrix, a cellulosic polysaccharide obtained from sugarcane molasses by bacterial synthesis [18].…”

Section: Bio-nail Fabricationmentioning

confidence: 99%

Section: Bio-nail Fabricationmentioning

confidence: 99%

See 1 more Smart Citation

BIO-NAIL: a bacterial cellulose dressing as a new alternative to preserve the nail bed after avulsion

Pinto

Ferraz-Carvalho

et al. 2020

J Mater Sci: Mater Med

“…It has been studied in several areas of medicine and gained prominence for having adequate characteristics and promising results when used as a dressing and biological graft [14][15][16] . It has wide biomedical applicability, such as nail prosthesis, tympanic graft, in the postoperative period of hypospadias correction, in the treatment of pressure injuries, also presenting ideal properties as a dressing [15][16][17][18] . This integrative review (IR) aims to describe the healing effect of bacterial cellulose in the treatment of lower limb ulcers.…”

Section: Resultsmentioning

confidence: 99%

Bacterial cellulose biomaterials for the treatment of lower limb ulcers

Filho

Silva

et al. 2023

Rev. Col. Bras. Cir.

Chronic ulcers of the lower limbs are common and recurrent, especially in the elderly population, they are disabling injuries that generate a great socioeconomic burden. This scenario encourages the development of new, low-cost therapeutic alternatives. The present study aims to describe the use of bacterial cellulose in the treatment of lower limb ulcers. This is an integrative literature review, carried out in the PubMed and Science Direct databases by associating the descriptors, with the inclusion criteria being clinical studies in the last 5 years, available in full in English, Portuguese and Spanish. Five clinical trials were analyzed and the main therapeutic effects obtained in the experimental groups that used bacterial cellulose dressings were a reduction in the area of the wounds, one of the studies showed a reduction of 44.18cm2 in the area of the wound, the initial lesions measured on average 89.46cm2 and at the end of the follow-up, they had an average of 45.28cm2, since the reduction in pain and the decrease in the number of exchanges were advantages described in all groups that used the BS. It is concluded that BC dressings are an alternative for the treatment of lower limb ulcers, their use also reduces operational costs related to the treatment of ulcers.

“…Que vem sendo estudado em diversas áreas da medicina e ganhou destaque por possuir características adequadas e resultados promissores quando utilizada como curativo e enxerto biológico [14][15][16] . Possui vasta aplicabilidade biomédica como prótese ungueal, enxerto timpânico, no pós cirúrgico da correção de hipospádia, no tratamento de lesões por pressão apresentando também propriedades ideais como curativo [15][16][17][18] . Portanto, a presente revisão integrativa (RI) tem como objetivo descrever o efeito cicatrizante da celulose bacteriana no tratamento de úlceras de membros inferiores.…”

Section: Artigo De Revisãounclassified

Biomateriais de celulose bacteriana para o tratamento de úlceras de membros inferiores

Filho

Silva

et al. 2023

Rev. Col. Bras. Cir.

RESUMO As úlceras crônicas de membros inferiores são comuns e recorrentes principalmente na população idosa, são lesões incapacitantes e que geram grande ônus socioeconômico. Tal cenário incentiva o desenvolvimento de novas alternativas terapêuticas e de baixo custo. O presente estudo tem como objetivo descrever o uso da celulose bacteriana no tratamento de úlceras de membros inferiores. Trata-se de uma revisão integrativa da literatura, realizada nas bases de dados PubMed e Science Direct por meio da associação dos descritores, tendo como critério de inclusão estudos clínicos nos últimos 5 anos, disponíveis na integra em inglês, português e espanhol. Cinco ensaios clínicos foram analisados e os principais efeitos terapêuticos obtidos nos grupos experimentais que utilizaram os curativos de celulose bacteriana foram redução da área das feridas, um dos estudos apontou uma redução de 44,18cm2 da área da ferida, as lesões iniciais mediam em média 89,46cm2 e ao término do acompanhamento apresentaram uma média de 45,28cm2, já a redução da dor e diminuição do número de trocas foram vantagens descritas em todos os grupos que utilizaram a CB. Conclui-se que os curativos de CB são uma alternativa para o tratamento das úlceras de MMII, sua utilização reduz também os custos operacionais relacionados ao tratamento de úlceras.