Unilateral Systematized Achromic Naevus

In vivo reflectance confocal microscopy for the differential diagnosis between vitiligo and nevus depigmentosus

“…All patients were examined by a specialized dermatologist to exclude other hypopigmentary disorders. A diagnosis of vitiligo was based on medical history, physical examination, and a Wood’s lamp examination, and the diagnosis of ND was based on the clinical criteria proposed by Coupe 8 . Sixty patients (32 females and 28 males), age ranging from 2 to 69 years, with localized vitiligo and a median duration of six years (range from 10 months to 19 years) entered the study.…”

Disorders of pigmentation

“…6,370 In one study, nearly one-half had only one lesion, but a fifth of patients had more than 10 lesions. 334,372 In the majority of cases the lesions are present at birth or appear in early childhood. 334,372 In the majority of cases the lesions are present at birth or appear in early childhood.…”

Clinical and histopathologic characteristics of nevus depigmentosus

“…In each patient, the diagnosis of ND was determined by clinical diagnostic criteria proposed by Coupe 4 and Wood's light examination. The clinical data compiled included sex, age, age of onset, number of lesions, involved sites, shape and pattern of lesions, and associated systemic disease.…”

“…Primary antibodies included S-100 protein (Dako Corp, Carpinteria, Calif), MART-1 (Neomarker, Fremont, Calif), NKI/ beteb (Monosan, Uden, The Netherlands), CD1a (Dako Corp), CD3 (Novocastra, Newcastle, United Kingdom), CD20 (Dako Corp), and CD68 (Dako Corp). In addition to the criteria of Coupe 4 and Wood's light examination, we excluded vitiligo histologically in the screening step by performing Fontana-Masson and NKI/beteb stain.…”