This article deals with a three-dimensional unsteady numerical simulation of the unsteady rotor—stator interaction in a HP turbine stage. The numerical approach consists of a computational fluid dynamics (CFD) parallel code, based on an upwind total variation diminishing finite volume approach. The computation has been carried out using a sliding plane approach with hybrid unstructured meshes and a two-equation turbulent closure. The turbine rig under investigation is representative of the first stage of aeronautic gas turbine engines. A brief description of the cascade, the experimental setup, and the measuring technique is provided. Time accurate CFD computations of pressure fluctuations and Nusselt number are discussed against the experimental data.