Untersuchungen zur Pathogenese der anaphylaktischen Reaktionen nach Thiaminapplikation

Blum, Kai; Kasemir, H.; Scharfe, W.

doi:10.1007/978-3-642-85449-1_495

Cited by 3 publications

(3 citation statements)

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“…The first column of table 3 reports some estimates by Ulrich Blum and Simone Scharfe and documents the great strides that have been made, especially when the initial conditions are considered. 13 On top of that, infrastructure in eastern Germany was modernized to the tune of more than DM 140 billion during 1992-98; this amounted to a third of all infrastructure spending in all of Germany over that period, raising it to western German levels in many consumption-related categories. 14 Table 4 documents the same point at the microeconomic level, also showing the striking similarities in household behavior in the two regions after an initial adjustment period.…”

Section: How Much Convergence Has Occurred?mentioning

confidence: 99%

“…Between-group inequality refers to inequality between groups of workers with the same observable characteristics, whereas within-group inequality reflects inequality within these groups. The last two panels of table 13 show results based on mean regressions for east and west, using the set of control variables including tenure, firm size, industry, and part-time status. Eastern men and women have similar increases in the within-group differential of 0.13 to 0.15, with the result that within-group inequality is 0.69 for both sexes.…”

Section: Is the Wage Structure Inappropriate?mentioning

confidence: 99%

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From Reunification to Economic Integration: Productivity and the Labor Market in Eastern Germany

Burda¹,

Hunt²

2001

eca

216

177

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IT IS DIFFICULT TO FIND A MORE dramatic episode of economic dislocation in peacetime during the twentieth century than that associated with the reunification of Germany. It is a sad irony of history that the plucky East Germans who toppled the dictatorship of the proletariat in the bloodless revolution of 1989 were rewarded with an economic bloodletting on such a vast scale. From 1989 to 1992, GDP in the former German Democratic Republic declined by roughly 30 percent, value added in industry by more than 60 percent, and employment by 35 percent. During the same period, unemployment rose from officially zero to more than 15 percent. That figure, moreover, is based on registered unemployment only; joblessness

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Section: How Much Convergence Has Occurred?mentioning

confidence: 99%

Section: Is the Wage Structure Inappropriate?mentioning

confidence: 99%

From Reunification to Economic Integration: Productivity and the Labor Market in Eastern Germany

Burda¹,

Hunt²

2001

eca

216

177

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“…Als zweites wird für den Pathomechanismus der möglichen Thiaminanaphylaxie vermutet, dass diese durch galenische Verunreinigungen der parenteralen Präparationen hervorgerufen wird. Dazu haben Blum und Kollegen [25] handelsüblich erhältliches Thiamin zur parenteralen Injektion chromatographisch aufgetrennt und einen ¹Nebenfleckª erhalten, der bei allen 4 Probanden nach intrakutaner Injektion eine Erythem-und Papelbildung hervorrief, während das so isolierte Thiamin weder bei den beiden Patienten mit vorherigen Anaphylaxie-Reaktionen noch bei den Kontrollpersonen eine Intrakutanreaktion hervorrief. Es wurde ein primär Histamin-vermittelter Prozess angenommen.…”

Section: Nebenwirkungen ± Die Gefürchtete Anaphylaxieunclassified

Die Thiaminbehandlung in der Psychiatrie und Neurologie

Hinze-Selch¹,

Weber²,

Zimmermann³

et al. 2000

Fortschr Neurol Psychiatr

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Every physician knows that alcohol dependence, alcohol withdrawal and Wernicke-Korsakow-syndrome require substitution with thiamine, in acute stages even parenterally. This would be trivial if there was not the widespread fear of anaphylactic, even lethal reactions to parenteral thiamine application. The present article reviews the literature published on thiamine since 1936, when the first synthetic, parenteral thiamine preparation became available, and, on this basis, tries to give practical advice and therapeutic regimens for the treatment of thiamine deficiency states. Controlled clinical studies on indications and differential thiamine therapy have not been published. From the data that are available, the following conclusions can be drawn: 1) Acute mortality of Wernicke-Korsakow-syndrome is about 20%. 2) Oral thiamine is safe. 3) The risk for an anaphylactic shock due to parenteral thiamine administration is below 1 to 100,000. 4) Not only alcohol but any condition with either increased metabolic need (pregnancy, consuming diseases) or deficient nutrition (including eating disorders) can lead to thiamine deficiency. Therefore, we suggest: 1) Oral thiamine substitution with at least 50 mg per day and supply of a sufficient and complete diet should be given to any person that might be at risk for thiamine deficiency. 2) Any patient suspicious for acute thiamine deficiency needs to be treated under inpatient conditions and there needs to receive 50 to 100 mg thiamine intravenously 3 to 4 times a day. 3) General practitioners, psychiatrists and neurologists should take care of the oral supplementation of thiamine, sufficient nutrition, and they are the physicians to diagnose early stages of thiamine deficiency.

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Acute and Chronic Alcohol-Related Disorders

Thier

2003

Neurological Disorders

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Untersuchungen zur Pathogenese der anaphylaktischen Reaktionen nach Thiaminapplikation

Cited by 3 publications

References 1 publication

From Reunification to Economic Integration: Productivity and the Labor Market in Eastern Germany

From Reunification to Economic Integration: Productivity and the Labor Market in Eastern Germany

Die Thiaminbehandlung in der Psychiatrie und Neurologie

Acute and Chronic Alcohol-Related Disorders

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