Upregulation of Basic Fibroblast Growth Factor in Human Periapical Lesions

Immunohistochemical Evaluation of Angiogenesis and Tryptase-positive Mast Cell Infiltration in Periapical Lesions

“…Thus, we believe that the differential expression of CD105 supports angiogenic activity and tissue remodeling. Moreover, in addition to tryptase, the expression of endothelial markers in periapical lesions is consistent with the presence of various angiogenic factors such as b-FGF, TNF-a, TGF-a, TGF-b1, and VEGF (33)(34)(35)(36).…”

Immunoexpression of vascular endothelial growth factor in periapical granulomas, radicular cysts, and residual radicular cysts

“…3 By definition, residual radicular cysts (RRCs) represent RCs that are inadvertently left behind after the extraction of the involved tooth. 4,5 Vascular endothelial growth factor (VEGF) is a potent proangiogenic cytokine secreted by many cell types which presents several pivotal functions in physiologic and pathologic angiogenesis. [6][7][8] VEGF acts on the vasculature by inducing the proliferation, differentiation, and migration of vascular endothelial cells.…”

Essential factors associated with hepatic angiogenesis

“…Acidic fibroblast growth factor (aFGF) participates in various cellular functions including proliferation, differentiation, angiogenesis, and cell migration in vitro (Marsden et al, 1992). The VEGF stimulates endothelial cells to produce a heparin-binding basic fibroblastic growth factor (bFGF) (Pallares et al, 2006), which further stimulates endothelial cell proliferation and migration in vitro and angiogenesis in vivo (Moldauer et al, 2006). The bFGF and VEGF showed synergistic effects (Yoshiji et al, 2002b).…”