Uptake and toxicological effects of pharmaceutical active compounds on maize

Hammad, Hafiz Mohkum; Zia, Farheen; Bakhat, Hafiz Faiq; Fahad, Shah; Ashraf, Muhammad; Wilkerson, Carol Jo; Shah, Ghulam Mustafa; Nasim, Wajid; Khosa, Ikramulah; Shahid, Muhammad

doi:10.1016/j.agee.2018.02.022

Cited by 39 publications

(11 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Maize (Zea mays L.) is effectively grown in Pakistan from below sea level (from 58 °N to 40 °S) to higher altitudes (3300 m) in a subtropical and temperature-controlled environment . After rice and wheat, maize has been dubbed the king of grain crops. − Maize is grown on an area of around 896 thousand hectares in Pakistan, with a yearly mass production of 4.9 million tons of grains. , It is widely cultivated in Khyber Pakhtunkhwa (KPK) and Punjab, accounting for around 98% of Pakistan’s total production. ,− It is grown on around 1.11 million hectares of land and has an average yield of 3.62 tha –1 . Maize is planted in rain-fed areas for the remaining 34%, with around 66% of the crop being grown in irrigated areas .…”

Section: Introductionmentioning

confidence: 99%

“…29 After rice and wheat, maize has been dubbed the king of grain crops. 30 − 33 Maize is grown on an area of around 896 thousand hectares in Pakistan, with a yearly mass production of 4.9 million tons of grains. 34 , 35 It is widely cultivated in Khyber Pakhtunkhwa (KPK) and Punjab, accounting for around 98% of Pakistan’s total production.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Efficacy of Naphthyl Acetic Acid Foliar Spray in Moderating Drought Effects on the Morphological and Physiological Traits of Maize Plants (Zea maysL.)

Ullah

Khan

et al. 2023

ACS Omega

View full text Add to dashboard Cite

The threat of varying global climates has greatly driven the attention of scientists, as climate change increases the odds of worsening drought in many parts of Pakistan and the world in the decades ahead. Keeping in view the forthcoming climate change, the present study aimed to evaluate the influence of varying levels of induced drought stress on the physiological mechanism of drought resistance in selected maize cultivars. The sandy loam rhizospheric soil with moisture content 0.43–0.5 g g–1, organic matter (OM) 0.43–0.55 g/kg, N 0.022–0.027 g/kg, P 0.028–0.058 g/kg, and K 0.017–0.042 g/kg was used in the present experiment. The findings showed that a significant drop in the leaf water status, chlorophyll content, and carotenoid content was linked to an increase in sugar, proline, and antioxidant enzyme accumulation at p < 0.05 under induced drought stress, along with an increase in protein content as a dominant response for both cultivars. SVI-I & II, RSR, LAI, LAR, TB, CA, CB, CC, peroxidase (POD), and superoxide dismutase (SOD) content under drought stress were studied for variance analysis in terms of interactions between drought and NAA treatment and were found significant at p < 0.05 after 15 days. It has been found that the exogenous application of NAA alleviated the inhibitory effect of only short-term water stress, but yield loss due to long-term osmotic stress will not be faced employing growth regulators. Climate-smart agriculture is the only approach to reduce the detrimental impact of global fluctuations, such as drought stress, on crop adaptability before they have a significant influence on world crop production.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Efficacy of Naphthyl Acetic Acid Foliar Spray in Moderating Drought Effects on the Morphological and Physiological Traits of Maize Plants (Zea maysL.)

Ullah

Khan

et al. 2023

ACS Omega

View full text Add to dashboard Cite

show abstract

“…It has been shown that NSAIDs influence the plant's development. Hammad et al [27] discovered that paracetamol has a detrimental effect on Zea mays growth and development. When the dose of paracetamol was raised, the accumulation of paracetamol in maize grain and root grew linearly; however, the protein content of the grain was not impacted by the dose increase.…”

Section: Introductionmentioning

confidence: 99%

Influence of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) on Photosynthetic Parameters and Secondary Metabolites of Plants from Fabaceae Family

et al. 2022

View full text Add to dashboard Cite

Nonsteroidal anti-inflammatory medications (NSAIDs) are commonly used painkillers, anti-inflammatory agents, and fever reducers. They arrive in the environment from municipal wastewater and/or agriculture waste, affecting growing plants. In our study, the impact of NSAIDs, namely, diclofenac, indomethacin, naproxen, and paracetamol, on four plant species from the Fabaceae family (Cicer arietinum, Pisum sativum, Lens culinaris, and Vicia faba) was tested. The assimilation rate and stomatal conductance decreased for all plants treated with NSAIDs. Chlorophyll and carotenoid contents in the leaves of plants under stress declined by more than 15% compared with the control plants, while the flavonoids and total phenols decreased to a lesser extent. In contrast, the plants treated with NSAIDs emit terpenes and green leaf were volatile, at a level of some nmol m−2 s−1, which could influence the atmospheric reaction and ozone formation.

show abstract

“…Soil exposure to PhACs can suppress soil microbial activities or decrease microbial biomasses, and also increase the occurrence of resistance genes in the ecosystem (McKinney et al, 2018;Wang, Wang, et al, 2018). In addition, root uptake of PhACs and their transformation products by edible plants and/or leaching of PhACs to the groundwater also increase the chronic exposure of humans to PhACs (Hammad et al, 2018;Spielmeyer et al, 2017). Sorption of the PhACs to soil is a major determinant regarding the fate and mobility of PhACs in subsurface systems (Wang & Wang, 2015).…”

Section: Introductionmentioning

confidence: 99%

Interaction of pig manure-derived dissolved organic matter with soil affects sorption of sulfadiazine, caffeine and atenolol pharmaceuticals

Zhang

Tang

Thiele‐Bruhn

2021

Environ Geochem Health

View full text Add to dashboard Cite

Pharmaceutically active compounds (PhACs) released into the environment have an adverse impact on the soil and water ecosystem as well as human health. Sorption of PhACs by soils and its potential modification through introduced DOM in the applied animal manure or treated wastewater (TWW) determines the mobility and environmental relevance of PhACs. Sulfadiazine, caffeine and atenolol were selected as target PhACs to investigate their sorption behaviors by five selected arable soils in the absence and presence of pig manure DOM. Sulfadiazine was least sorbed, followed by caffeine and atenolol according to the Freundlich sorption isotherm fit (soil average Kf [μg(1−n) mLn g−1] 4.07, 9.06, 18.92, respectively). The addition of manure DOM (31.34 mg C L−1) decreased the sorption of sulfadiazine and especially of caffeine and atenolol (average Kf 3.04, 6.17, 5.79, respectively). Freundlich sorption isotherms of the PhACs became more nonlinear in the presence of manure DOM (Freundlich exponent n changed from 0.74–1.40 to 0.62–1.12), implying more heterogeneous sorption of PhACs in soil–DOM binary systems. Sorption competition of DOM molecules with sulfadiazine and caffeine mostly contributed to their decreased soil sorption when DOM was present. In contrast, the formation of DOM–atenolol associates in the solution phase caused the largely decreased soil sorption of atenolol in the presence of DOM. It is suggested that DOM concentration (e.g., ≥ 60 mg C L−1) and its interaction with PhACs should be taken into consideration when assessing the environmental impact of land application of animal manure or irrigation with TWW.

show abstract

Uptake and toxicological effects of pharmaceutical active compounds on maize

Cited by 39 publications

References 49 publications

Efficacy of Naphthyl Acetic Acid Foliar Spray in Moderating Drought Effects on the Morphological and Physiological Traits of Maize Plants (Zea maysL.)

Efficacy of Naphthyl Acetic Acid Foliar Spray in Moderating Drought Effects on the Morphological and Physiological Traits of Maize Plants (Zea maysL.)

Influence of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) on Photosynthetic Parameters and Secondary Metabolites of Plants from Fabaceae Family

Interaction of pig manure-derived dissolved organic matter with soil affects sorption of sulfadiazine, caffeine and atenolol pharmaceuticals

Contact Info

Product

Resources

About