Use of 2-Octyl-Cyanoacrylate Skin Adhesive (Dermabond) for Wound Closure following Reduction Mammaplasty: A Prospective, Randomized Intervention Study

Nipshagen, Martine D.; Hage, J. Joris; Beekman, Werner H.

doi:10.1097/prs.0b013e318171524b

Cited by 51 publications

(35 citation statements)

References 26 publications

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“…However, there were minor woundhealing complications encountered in this series that were subjectively lower compared to our previous patient group in which we did not use Prineo TM . These were comparable to previously reported incidences of wound-healing complications [12]. However, this comparison was not performed on a statistical basis and is therefore rather anecdotal.…”

Section: Resultssupporting

confidence: 69%

“…Besides being time-consuming, intracutaneous sutures increase wound edge ischemia and inflammation, which play a major role in wound healing and final scar appearance. Therefore, alternative wound closure systems such as 2-octyl cyanoacrylate (Dermabond TM ) have been used with good success [10][11][12]. Recently, the Prineo TM wound closure system was introduced, representing the next generation of skin adhesives [13].…”

Section: Discussionmentioning

confidence: 99%

“…Usually closure of incisions in these operations is time-consuming due to the lengthy wounds that are typically encountered when using resorbable subcutaneous sutures and nonresorbable intracutaneous sutures. Thus, alternative skin closure systems such as 2-octyl cyanoacrylate (Dermabond TM ; Ethicon, Inc., Somerville, NJ, USA) have been introduced with good success and safety [10][11][12]. Prineo TM (Ethicon) is a new development in topical skin adhesives, combining a self-adhering, pressure-sensitive adhesive (PSA), polyester-based mesh for temporarily holding together the approximated skin edges of an incision and a 2-octyl cyanoacrylate liquid adhesive formulation for final skin closure.…”

mentioning

confidence: 99%

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Effective Wound Closure With a New Two-Component Wound Closure Device (Prineo™) in Excisional Body-Contouring Surgery: Experience in Over 200 Procedures

et al. 2011

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Background In excisional body-contouring surgery the surgeon is often confronted with time-consuming closure of long wounds. Recently, a new combination of a selfadhering mesh together with a liquid 2-octyl cyanoacrylate adhesive (Prineo TM ; Ethicon, Inc., Somerville, NJ, USA) has been introduced to replace intracutaneous running suture. Methods An observational study was undertaken to evaluate the efficacy of the new wound closure device in excisional body-contouring procedures between January 2008 and November 2010. Wound characteristics were recorded in a prospectively maintained database. Results During the study period, 224 procedures in 180 patients were undertaken. Twenty-seven patients had two subsequent operations and four patients had three subsequent operations. Application of the new device was easy and safe and patient satisfaction with the results was generally high. However, intense local allergic reactions were seen in 4 patients (1.8%), which necessitated early removal and topical corticosteroid treatment. Conclusions Prineo TM enables the surgeon to perform a quick and smooth skin closure, especially in long incisions frequently encountered in excisional body-contouring surgery. The application is fast and easy if basic guidelines are respected. Operating time is saved by eliminating the need for time-consuming intracutaneous running sutures. Removal is easy and painless for the patient. However, there is a potential for local allergic adverse effects of which the surgeon must be aware.

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Section: Resultssupporting

confidence: 69%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Effective Wound Closure With a New Two-Component Wound Closure Device (Prineo™) in Excisional Body-Contouring Surgery: Experience in Over 200 Procedures

et al. 2011

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“…6,7 The OCA tissue adhesives are supplied as monomers in a liquid form. They polymerise on contact with tissue anions, forming a strong bond that holds the opposed wound edges together.…”

Section: Introductionmentioning

confidence: 99%

A prospective randomised controlled trial of octylcyanoacrylate tissue adhesive and standard suture for wound closure following breast surgery

Chen

Choi²,

Suen

et al. 2016

Hong Kong Med J

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“…5 Vascularized flaps are reported to be more reliable, have lower rates of infection, and allow earlier bone integration. 3 …”

Section: Discussionmentioning

confidence: 99%

Use of Composite Osteotemporoparietal Fascia Flap for Midface Reconstruction After En Bloc Resection of Squamous Cell Carcinoma Involving the Zygomaticomaxillary Complex

Lee

Kenning

Pinheiro‐Neto

2016

Plastic and Reconstructive Surgery - Global Open

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Summary:The osteotemporoparietal fascia flap (OTPFF) has been used for bony defects, especially on the maxilla and orbital floor. However, there are limited reports about the reconstruction of the zygoma. We report the use of composite OTPFF for reconstruction of zygomaticomaxillary complex. The patient had undergone zygomaticomaxillary complex reconstruction with composite OTPFF because of the resection of recurrent postradiation tumor. Extratemporoparietal fascia was harvested and rotated to cover the medullary surface of the bone flap. Flap was successfully transferred with complete bone integration. There were no surgical complications and excellent cosmetic result. The patient is free of disease 12 months post surgery. The OTPFF seems to be a good option in zygomatic reconstruction, even in previously irradiated fields. Utilization of extratemporoparietal fascia to cover the medullary surface of the bone flap has potential to be an advantageous technique to minimize bone exposure and improve flap integration.

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Use of 2-Octyl-Cyanoacrylate Skin Adhesive (Dermabond) for Wound Closure following Reduction Mammaplasty: A Prospective, Randomized Intervention Study

Abstract: The authors conclude that 2-octyl-cyanoacrylate is a sound alternative for wound closure.

Cited by 51 publications

References 26 publications

Effective Wound Closure With a New Two-Component Wound Closure Device (Prineo™) in Excisional Body-Contouring Surgery: Experience in Over 200 Procedures

Effective Wound Closure With a New Two-Component Wound Closure Device (Prineo™) in Excisional Body-Contouring Surgery: Experience in Over 200 Procedures

A prospective randomised controlled trial of octylcyanoacrylate tissue adhesive and standard suture for wound closure following breast surgery

Use of Composite Osteotemporoparietal Fascia Flap for Midface Reconstruction After En Bloc Resection of Squamous Cell Carcinoma Involving the Zygomaticomaxillary Complex

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