Use of Acellular Dermal Matrix for Complicated Ventral Hernia Repair: Does Technique Affect Outcomes?

Jin, Judy; Rosen, Michael J.; Blatnik, Jeffrey A.; McGee, Michael F.; Williams, Christina P.; Marks, Jeffrey M.; Ponsky, Jeffrey L.

doi:10.1016/j.jamcollsurg.2007.06.012

Cited by 216 publications

(115 citation statements)

References 17 publications

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“…Also, in this study, it was determined that more recurrence developed after 6 months in the group that was not treated with PRP. In terms of incisional hernia recurrence rates in experimental work, since it has not been recommended much due to working disadvantages (the disproportion of the incision length to the size of the rat, difficult surgical technique), there are very few publications on this subject and these studies are found more among human studies 25,26 .…”

Section: Discussionmentioning

confidence: 99%

Effects of platelet rich plasma on fascial healing in rats with fecal peritonitis

et al. 2016

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PURPOSE:To evaluate the effects of platelet rich plasma (PRP) on the healing of fascia wherein peritonitis has been created. METHODS:Twenty eight Wistar Albino rats were divided into four groups. Only a primary fascial repair following laparotomy was performed on Group 1, a primary fascial repair performed and PRP treatment applied following laparotomy on Group 2, and a fecal peritonitis created following laparotomy and a primary fascial repair carried out on Group 3. A fecal peritonitis was created following laparotomy and primary fascial repair and PRP treatment on the fascia was carried out on Group 4. RESULTS:TNF-α was found to be significantly lower in the control group (Group 1). It was detected at the highest level in the group in which fecal peritonitis was created and PRP applied (Group 4). TGF-β was determined as being significantly higher only in Group 4. Histopathologically, the differences between the groups in terms of cell infiltration and collagen deposition were not found to be significant. CONCLUSION:When platelet rich plasma was given histologically and biochemicaly as wound healing parameters cellular infiltration, collagen accumulation, and tissue hydroxyiproline levels were not increased but neovascularization, fibroblast activation and TNF Alfa levels were increased and PRP accelerated wound healing.

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Section: Discussionmentioning

confidence: 99%

Effects of platelet rich plasma on fascial healing in rats with fecal peritonitis

et al. 2016

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“…For this reason, the use of biological mesh in a bridging manner (inlay) provides a solution which is temporary but absolutely not definitive, requiring a future mesh implantation to definitively correct the defect [4] . On the other hand, when the biological mesh is fixed retromuscularly employing a sublay technique the recurrence rate seems comparable to other synthetic prosthesis [9,15] .…”

Section: Discussionmentioning

confidence: 99%

“…Bioprosthetic meshes have properties that may come close to ideal material. Recent studies have shown the use of acellular dermal allograft and porcine small intestine submucosa as valid solutions for complicated ventral hernia repair [4] . Bovine pericardium is largely employed in paediatric and heart surgery and has replaced dura madre patches as the standard biomaterial for the closure of anterior abdominal wall defects in omphaloceles and gastroschisis [5,6] .…”

Section: Introductionmentioning

confidence: 99%

Use of bovine pericardium graft for abdominal wall reconstruction in contaminated fields

D’Ambra¹,

Berti²,

Feleppa³

et al. 2012

WJGS

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AIM:To employ, in such conditions, a biological graft such as bovine pericardium that offers resistance to infection. METHODS:In our surgical department, from January 2006 to June 2010, 48 patients underwent abdominal wall reconstruction using acellular bovine pericardium; of these 34 patients had a contaminated wound due to diffuse peritonitis (complicated diverticulitis, bowel perforation, intestinal infarction, strangled hernia, etc. ) and 14 patients had hernia relapse on infected synthetic mesh. RESULTS:In our series, one patient died of multiorgan failure 3 d after surgery. After placement of the pericardium mesh four cases of hernia relapse occurred. CONCLUSION:Recurrence rate is similar to that of prosthetic mesh repair and the application of acellular bovine pericardium (Tutomesh ® , Tutogen Medical Gmbh Germany) is moreover a safe and feasible option that can be employed to manage complicated abdominal wall defects where prosthetic mesh is unsuitable.

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“…In patients in whom the rectus muscles still cannot be brought to the midline, a bridged mesh repair is required. Bridged mesh repairs have demonstrated higher recurrence and complication rates compared with nonbridged repairs and, are therefore, suboptimal, particularly with biologic mesh (19,20). Outcomes are significantly improved with a mesh reinforced repair, in which the fascial edges are closed completely over the mesh.…”

Section: Abstract: Hernia; Surgical Mesh; Tissue Engineering; Ventralmentioning

confidence: 99%

Surgical mesh for ventral incisional hernia repairs:Understanding mesh design

Rastegarpour¹,

Cheung²,

Vardhan³

2016

J Plastic Surgery

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Use of Acellular Dermal Matrix for Complicated Ventral Hernia Repair: Does Technique Affect Outcomes?

Cited by 216 publications

References 17 publications

Effects of platelet rich plasma on fascial healing in rats with fecal peritonitis

Effects of platelet rich plasma on fascial healing in rats with fecal peritonitis

Use of bovine pericardium graft for abdominal wall reconstruction in contaminated fields

Surgical mesh for ventral incisional hernia repairs:Understanding mesh design

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