Use of bovine lactoferrin for Helicobacter pylori eradication

Mario, F. Di; Aragona, Giovanni; Bò, N. Dal; Cavestro, Giulia Martina; Cavallaro, L.G.; Iori, Veronica; Comparato, G.; Leandro, Gioacchino; Pilotto, Alberto; Franzè, A.

doi:10.1016/s1590-8658(03)00409-2

Cited by 72 publications

(69 citation statements)

References 31 publications

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“…1 In the present multicentred study, both ITT and PP analyses showed that the eradication rate was higher than 89% for patients in the bLf adjuvant group, results that confirmed those in previous studies. 35,36 .…”

Section: Discussionmentioning

confidence: 99%

Bovine lactoferrin for Helicobacter pylori eradication: an open, randomized, multicentre study

Mario¹,

Aragona²,

Bò³

et al. 2006

Aliment Pharmacol Ther

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Section: Discussionmentioning

confidence: 99%

Bovine lactoferrin for Helicobacter pylori eradication: an open, randomized, multicentre study

Mario¹,

Aragona²,

Bò³

et al. 2006

Aliment Pharmacol Ther

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“…An additional therapeutic approach is to add bovine lactoferrin to an established eradication regimen (rabeprazol + clarithromycin + tinidazole). In a study of 150 patients, the eradication rate was 92% in the combination with bovine lactoferrin compared to 71% without 12 .…”

Section: Antimicrobial Agentsmentioning

confidence: 98%

Helicobacter Pylori: Current Status and Future Prospects

O’Mahony¹,

Vaira

Holton³

et al. 2004

Science Progress

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Helicobacter pylori is a global pathogen that causes severe gastrointestinal diseases leading to a significant morbidity and mortality. There is an effective treatment for peptic ulcer disease, however, this is being compromised by an increase in the prevalence of antibiotic resistance. Although alternative rescue regimens have been advocated, the best strategy would be to prevent disease, especially in the case of gastric cancer for which there is still no treatment. One approach is to inhibit the first step in the pathogenic process-adhesion of the organism to the host tissue. Another and probably a better approach is vaccination, but clinical trials have so far been unsuccessful. There is still a large uncertainty in relation to how H. pylori causes disease. Knowledge from genomics, proteomics, and the relationship between polymorphism of the bacterium and the host, as well as the continuing investigation of the role played by important virulence factors in the outcome of the disease, will help both in understanding pathogenesis of disease and in the design of the best vaccine.

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“…14,15 Peynir altı suyu konsantratlarının Escherichia coli, Salmonella typhimurium, Shigella dysenteriae, Listeria monocytogenes, Bacillus stearothermophilus, Bacillus subtilis, Micrococcus luteus, Pseudomonas aeruginosa, Listeria monocytogenes, Candida albicans ve özellikle de Helicobacter pylori eradikasyonunda etkin olduğu kanıtlanmıştır. [16][17][18][19] …”

Section: Anti̇mi̇krobi̇yalunclassified

Whey Protein: A New Supportive and Regenerative Therapy Chance Ignored in Veterinary Medicine: Review

Dalğın¹,

Yücel²

2016

Turkiye Klinikleri J Vet Sci

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Ö ÖZ ZE ET T Peynir altı suyu, daha önceleri, peynir yapımının bir atık ürünü olarak ele alınmakta idi, fakat son yıllarda bileşimi ortaya konularak, içeriği oluşturan aminoasit, immünglobulin, büyüme faktörleri gibi maddelerin antimikrobiyal, antiviral, antifungal, epitelizan, immün stimülan, rejeneratif gibi birçok terapötik etkileri tanımlanmıştır. Beşerî hekimlikte peynir altı suyu immün stimülasyon amacıyla özellikle yaş-lılarda iskemik atakta, "human immunodeficiency virus" (HIV) enfeksiyonunda, pek çok hastalıkta antimikrobiyal amaçlı (Escherichia coli, Salmonella typhimurium, Shigella dysenteriae, Listeria monocytogenes, Bacillus stearothermophilus, Bacillus subtilis, Micrococcus luteus, Pseudomonas aeruginosa, Listeria monocytogenes, Candida albicans ve Helicobacter pylori), egzersiz ve sporcularda kas yapımında, gastrointestinal sistem hastalıklarında, kanser hastalarında, osteoporözde, ağız ve diş sağlığında, depresyon, stres ve kozmetik sektörü gibi pek çok alanda kullanılmaktadır. Oysa güncel literatür tarandığında, bu ürünün maalesef veteriner hekimlik alanında çok fazla araştırılmamış, özellikle de rutin kullanıma girmekten çok uzak olduğu görülmektedir. Doğal ve maliyeti düşük olan peynir altı suyunun, ister toz hâ-linde, ister taze sıvı hâlde; barsak hastalıkları, köpeklerin parvoviral enteritisi, yangısal barsak hastalığı, yenidoğan ve gelişme geriliği gösteren yavrular, viral, bakteriyel, paraziter hastalıklar, geriatri, kanser hastalığı gibi durumlarda destek ve rejeneratif tedavi yönünden değerlendirilmesi ile terapi başarısına önemli ölçüde katkı sağlayacağı kanaatindeyiz. Bu çalışmada, peynir altı suyunun içeriği, beşerî ve veteriner hekimlik sahasında kullanım alanları özetlenmiştir.A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Vey protein; veterinerlik bilimi; tedavi A AB BS S T TR RA AC CT T Whey was a waste product of cheese manufacturing previously, but in the last decades with the identification of its content, it is used in many areas of human medicine as a supportive element because of the antimicrobial, antiviral, antifungal, epithelialing, immune stimulant, regeneratif effects due to its amino acid, immune globuline, growth factors etc. components. Major areas whey proteins are used in human medicine are immune stimulation, ischemic attack especially in elderly, , human immunodeficiency virus (HIV) infection, in many disorders as antimicrobials (Escherichia coli, Salmonella typhimurium, Shigella dysenteriae, Listeria monocytogenes, Bacillus stearothermophilus, Bacillus subtilis, Micrococcus luteus, Pseudomonas aeruginosa, Listeria monocytogenes, Candida albicans and Helicobacter pylori), exercise and by sportsmen for muscle protein synthesis, gastrointestinal system disorders, neoplastic disorders, osteoporesis, oral and dental health, depression and stress and cozmetic areas. Unfortunately, current literature shows that this product has not been invesitigated and very far from clinical application in veterinary medicine. The authors opinion is that, this economically ...

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Use of bovine lactoferrin for Helicobacter pylori eradication

Cited by 72 publications

References 31 publications

Bovine lactoferrin for Helicobacter pylori eradication: an open, randomized, multicentre study

Bovine lactoferrin for Helicobacter pylori eradication: an open, randomized, multicentre study

Helicobacter Pylori: Current Status and Future Prospects

Whey Protein: A New Supportive and Regenerative Therapy Chance Ignored in Veterinary Medicine: Review

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