Use of fibrin adhesive for preventing pharyngocutaneous fistula in total laryngectomy

Park, Jaimie J; Chang, Crystal; Kwon, Daniel

doi:10.1016/j.amjoto.2020.102674

Cited by 7 publications

(2 citation statements)

References 22 publications

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“…(7) Prior radiation therapy, hypothyroidism, and poor nutritional status have been proposed as risk factors for fistula development. ( 8),(9),(10), (11) We hypothesized that drain migration from the pharyngeal closure bed would impact PCF formation or detection. Our analysis showed no difference in the incidence of complications between the EO and IE groups.…”

Section: Supplementary Informationmentioning

confidence: 99%

Surgical Drain Placement Technique and Its Effects Following Total Laryngectomy

Koshkareva

2023

JORR

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Objective: We aimed to determine whether securing Jackson-Pratt (JP) drains with suture both internally and externally (IE) vs. externally only (EO) after total laryngectomy affects drain migration and incidence or rate of postoperative complications. Study Design: Retrospective chart review. Setting: Single institution urban tertiary care center. Methods: Fifty-three patients who underwent total laryngectomy were reviewed retrospectively and categorized as IE or EO. Post-operative esophagograms were reviewed by 12 non-affiliated Otolaryngologists. Drain displacement, post-operative complication rates and time to detection of complication were compared. Results: Fewer radiographs (20.7%) were designated as "displaced" in the IE group compared to the EO group (30.4%) (p = 0.05). There was no difference in complication rates or median time to detect salivary leaks between the two groups. Conclusion:The utilization of an internal suture technique to secure surgical drains following total laryngectomy was associated with a decreased rate of drain migration. However, drain migration did not appear to affect complication rates or timing of detection of a salivary leak.

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Section: Supplementary Informationmentioning

confidence: 99%

Surgical Drain Placement Technique and Its Effects Following Total Laryngectomy

Koshkareva

2023

JORR

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“…Research has also shown that these adhesives often lead to longer wound healing span and higher infection rates due to poor mechanical properties, significantly limiting their clinical application [13,14]. In response to the above problems, a variety of hydrogel tissue adhesives (polyethylene glycol [15], alginate [16], acrylic acid (Aa) and other composite hydrogel tissue adhesives) have been researched and developed [17][18][19][20], which effectively enhanced the adhesion of the tissue interface and reduced the phase transformation time of the hydrogel. However, due to the complex preparation system and mechanical deformation caused by limb movement, it is difficult to ensure a stable connection between the adhesives and the skin interface [5,9].…”

Section: Introductionmentioning

confidence: 99%

Bio-inspired hydrogel-based bandage with robust adhesive and antibacterial abilities for skin closure

Wang

Ren

et al. 2021

Sci. China Mater.

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Although conventional suturing techniques are commonly used in assisting wound closure, they do pose limited conduciveness and may lead to secondary injury to wound tissues. Inspired by marine organism mussels, we designed and manufactured a bio-inspired hydrogel-based bandage with tough wet tissue adhesion to substitute traditional surgical suture, accelerate wound healing and avoid infection. Poly(γ-glutamic acid) was modified with 3,4-dihydroxyphenylalanine and glycidyl methacylate, then introduced into the acrylic acid- co -acrylamide hydrogel matrix with robust mechanical properties. The hydrogel bandage showed strong chemical linkage adhesion (70 ± 2.1 kPa), which is 2.8 times that of commercial tissue adhesive fibrin glue (25 ± 2.2 kPa). The hydrogel bandage can not only maintain the self-stability, but is also capable of self-tuning adhesive strength in the range of 14–70 kPa to achieve different adhesion effects by tuning constituent ratio. The bandage has desirable compression properties (0.7 ± 0.11 MPa) and tensile elongation (about 25 times), which ensures its resistance to damages, especially in joint spaces. Secondly, the bandage was endowed with antioxidant and endogenous broad-spectrum antibacterial properties with its catechol structure. Results also demonstrated excellent cell compatibility and blood compatibility, certifying its eligible biological safety profile. In a rat full-thickness cutaneous deficiency model, we can clearly observe that the bandage possesses the ability to promote wound healing (only need 6 days). Above all, this research provides a new strategy for the emergency treatment of liver hemostasis and myocardial repair during disaster rescue. Supplementary information Experimental details and supporting data are available in the online version of the paper10.1007/s40843-021-1724-8.

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Total Laryngectomy

Wierzbicka

Jackowska

2022

Textbook of Surgery of Larynx and Trachea

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Use of fibrin adhesive for preventing pharyngocutaneous fistula in total laryngectomy

Cited by 7 publications

References 22 publications

Surgical Drain Placement Technique and Its Effects Following Total Laryngectomy

Surgical Drain Placement Technique and Its Effects Following Total Laryngectomy

Bio-inspired hydrogel-based bandage with robust adhesive and antibacterial abilities for skin closure

Total Laryngectomy

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