Uterine Angiomyolipoma: A Case Report, Differential Diagnosis with Pecoma and Review of the Literature

Abstract

Angiomyolipomas are benign mesenchymal neoplasms, presenting with a variable mixture of adipose tissue, smooth muscle and vascular component. Although they are typically found in the kidneys, many cases of extrarenal angiomyolipomas have been reported. They are extremely rarely present in the uterus. We describe a case of a 56-year-old woman, operated on for leiomyoma. Total laparohysterectomy and bilateral adnexectomy was performed. After histological and immunohistochemical examination, the final diagnosis of uterine angiomyolipoma was made. Renal and extrarenal angiomyolipomas are compared in regard to clinical and morphological aspect and their difference from PEComas is dicussed. PEComas have been defined during the last decade and there are still issues regarding terminological clarity and overlapping.

Uterine angiomyolipoma: A case report of an unusual entity

“…1,2 Totev et al have suggested that an epithelioid AML is a kind of PEComa and hence, advised to do melanocytic markers in all uterine mesenchymal tumors with epithelioid appearance. 9,10 Surgical resection is the mainstay of treatment for uterine AML. Most cases are treated by total abdominal hysterectomy with or without salphingooophorectomy.…”