Utility of Fine Needle Aspiration in HIV–Positive Patients with Corresponding CD4 Counts

Grossl, Norman A.; Mosunjac, Mario; Wallace, Timothy M.

doi:10.1159/000332708

Cited by 21 publications

(21 citation statements)

References 22 publications

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“…In the study conducted by Grossl et al, 17 CD4 counts mean in Acute suppurative inflammation, Granulomatous inflammation, Reactive lymph nodes, malignant lymphomas and suspicious for Kaposi sarcoma were 330, 145, 237, 105, 77/mm respectively.…”

Section: Cd4 Count In Relation To Lesionsmentioning

confidence: 87%

Study of Prevalence of Granulomatous Lymphadenitis in Individuals Affected With Hiv Infection

Rao¹,

Aparna²,

Murthy³

et al. 2017

jemds

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BACKGROUNDPrevalence of Granulomatous lymphadenitis in human immune deficiency virus infection is increasing drastically in developing countries, particularly in India. In the present study, an attempt has been made to find an association of Granulomatous lymphadenitis in human immune deficiency virus infection in humans.The aim of this study is to correlate the FNAC finding with clinical, radiological and morphological patterns like correlation with findings and the CD4 count, relation of Mantoux to lymph nodes and relation with x-ray findings. MATERIALS AND METHODSA descriptive study done in 100 adult patients, aimed to study the prevalence of tuberculous lymphadenitis by cytological patterns in lymph nodes of HIV sero-positive patients by collecting and studying material through FNAC and clinical importance by Mantoux and x-ray findings. Patients attending Government General Hospital, ACSR GMC, Nellore who was not on ATT or ART were chosen for the study. RESULTSVarious lesions were observed in this study. Granulomatous lymphadenitis was observed in 74 cases, reactive lymphadenitis was seen in 22 cases and acute suppurative lymphadenitis was seen in 3 cases. One case has shown secondary deposits of squamous cell carcinoma. CONCLUSIONFNAC is a relatively inexpensive initial investigative technique important for assessing the cause of lymphadenopathy in HIV patients; allows a rapid diagnosis obviating the need for surgery and enabling swift treatment to be undertaken where necessary. Universal safety precautions must be strictly followed. The method is accurate, cost effective and acceptable to patients. TB is the major opportunistic infection, which could be detected in both symptomatic and asymptomatic individuals and even in tiny nodes. There was strong association with Mantoux and x-ray for diagnosing Granulomatous lesions. KEYWORDS

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Section: Cd4 Count In Relation To Lesionsmentioning

confidence: 87%

Study of Prevalence of Granulomatous Lymphadenitis in Individuals Affected With Hiv Infection

Rao¹,

Aparna²,

Murthy³

et al. 2017

jemds

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“…2,3 Other investigators have noted the usefulness of culture of FNAB in HIV positive patients. 4 One study of 26 patients with acquired immunodeficiency syndrome (AIDS) noted that 9 of the 26 (35%) FNAB cultures yielded a new diagnosis that initiated a change in therapy. 5 Our study is in keeping with these results, as culture of FNAB in HIV patients resulted in positive cultures for either Mycobacterium tuberculosis or Mycobacterium avium-intracellulare complex in 7 of the 23 clinically significant cases.…”

Section: Discussionmentioning

confidence: 99%

Clinical significance of cultures collected from fine‐needle aspiration biopsy

Granville

Laucirica

Verstovsek

2008

Diagnostic Cytopathology

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The rate of positive cultures in fine-needle aspiration biopsy (FNAB) specimens is evaluated, and the value of submitting FNAB culture is assessed. Review of 3,300 FNAB specimens from 2,416 patients were tabulated for culture results, when obtained from the FNAB material. For positive culture results, clinical impact was assessed. Of 3,300 FNAB specimens and 2,416 patients, 185 had cultures performed (6% of specimens, 8% of patients). Of the 185 cultured specimens, 63 (34%) were positive and 122 (66%) were negative. Of the 63 positive cultures, 23 (12% of all FNAB cultures) had a significant impact on patient care. In our institution the FNA culture rate is 6%. When cases with clinical or microscopic suspicion of infection are cultured, 34% are positive for aerobic or anaerobic bacteria, mycobacteria or fungus. Culture in FNA specimens is a useful adjunct to diagnosis and impacts care in 12% of patients cultured at FNAB. This method can be used to triage patients with suspected infectious diseases and can aid in managing patients who may have recurrent infections.

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“…However, the diagnosis often is difficult. [7][8][9] If it is in doubt, molecular demonstration of human herpesvirus-8 (HHV-8) DNA could be a useful adjunct. 10 A few cases of KS involving the thyroid in immunocompromised patients have been reported, 1,2 but there have been no prior cases in which the diagnosis of thyroid KS has been rendered by FNA.…”

Section: Discussionmentioning

confidence: 99%

Simultaneous Cytomegalovirus Infection and Kaposi’s Sarcoma of the Thyroid Diagnosed by Fine Needle Aspiration in an AIDS Patient

Zhang¹,

el-Sahrigy²,

Elhosseiny³

et al. 2003

Acta Cytologica

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Utility of Fine Needle Aspiration in HIV–Positive Patients with Corresponding CD4 Counts

Cited by 21 publications

References 22 publications

Study of Prevalence of Granulomatous Lymphadenitis in Individuals Affected With Hiv Infection

Study of Prevalence of Granulomatous Lymphadenitis in Individuals Affected With Hiv Infection

Clinical significance of cultures collected from fine‐needle aspiration biopsy

Simultaneous Cytomegalovirus Infection and Kaposi’s Sarcoma of the Thyroid Diagnosed by Fine Needle Aspiration in an AIDS Patient

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