The influence of surface irradiation of GaAs with a KrF excimer laser on the magnitude of the quantum well intermixing (QWI) effect has been investigated on GaAs/AlGaAs and GaAs/AlGaAs/InAlGaAs QWs heterostructures. The selective area irradiation through a SiO x mask was carried out in an atmospheric environment. Following the 1000 pulses irradiation at 100 mJ/cm 2 , the samples were annealed in a rapid thermal annealing furnace at 900 ºC. Photoluminescence mapping and cathodoluminescence measurements show that significant laser-induced suppression of the QWI process can be achieved with lateral resolution of the order of 1 m.