Vacunas frente al virus de la varicela zóster

Salleras, L.; Salleras, M.; Soldevila, Núria; Prat, A.; Garrido, P.; Domı́nguez, Àngela

doi:10.1016/j.eimc.2015.05.005

Cited by 5 publications

(13 citation statements)

References 121 publications

(181 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[1][2][3][4][5]7 Outbreaks in schools have been observed with a single dose and coverage close to 99%. 5 Also with a single dose, the age of varicella onset may be delayed.…”

Section: Discussionmentioning

confidence: 99%

“…The bibliography even agrees that this disease is more severe in adults. 1,3,7 The vaccine effectiveness is very high; public immunization campaigns promoting two doses may help to interrupt varicella transmission in the long term. 3,7 It has also been seen that cost-effectiveness increases as the cost per dose reduces; the administration of two doses would be essential to optimize vaccination costs ( It is also evident, according to our results, that hospital discharges for varicella after 4 years of immunization will reduce to a half because 53% of hospitalizations occur in this age group, as described by the Gil-Prieto 14 group in 2014 based on communities where infants were vaccinated.…”

Section: Discussionmentioning

confidence: 99%

“…6 Some countries provide the measles, mumps, rubella and varicella (MMRV) vaccine to infants with the corresponding booster dose. 1,7 Varicella vaccine critics claim an increase in the incidence of herpes zoster. However, large population-based prospective studies have detected a reduction in the incidence of herpes zoster among vaccinated children compared to those who had wild-type varicella, although additional years of follow-up are required.…”

Section: Introductionmentioning

confidence: 99%

“…In adults, the rate of complications is 25 times higher. 1 Hospitalization expenses and workplace absenteeism due to varicella imply a large social disbursement. In the United States, it has been estimated that varicella is the most common cause of death attributed to vaccine-preventable diseases.…”

Section: Introductionmentioning

confidence: 99%

“…At present, in Spain, there are two live, attenuated virus (OKA strain) vaccines. 1,4 In the Autonomous Community of Aragón (1325 million inhabitants in 2014), the vaccine was introduced in the immunization schedule in 2007 for children aged 11 Original article administered free of charge by the Public Health System. Two vaccine doses provide an overall coverage of 100%, 5 and are very well-tolerated.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

A cost-benefit analysis of varicella vaccination in Aragón

Blasco

Pérez-Aramendía

2017

Arch Argent Pediat

View full text Add to dashboard Cite

Background. Varicella, a contagious and infectious disease that is usually benign in children, may become complicated among adults and vulnerable children and may even be life-threatening. There are effective vaccines. A retrospective study was conducted about costs and resulting hospitalizations related to this disease in the population of Aragón in the 2004-2014 period. Costs were compared to the expenses that would have been incurred if those people had received the vaccine and also to the expenses of vaccinating the 1-year-old population over the entire period. A cost-benefit analysis was done to assess the economic impact of varicella vaccination. Method. Data for the 11-year period were provided by the Autonomous Community of Aragón (Spain) and included annual varicella incidence, hospital discharges of varicella cases, costs of primary health care visits and hospitalizations for each year, costs of each workday as per the minimum annual salary and of drugs used). Capitalized costs were estimated and compared to capitalized expenses of vaccination, and a sensitivity analysis was performed. Results. A benefit-cost ratio of 1.6 was obtained considering that all children who had varicella had been vaccinated and had received a booster dose. A benefit-cost ratio of 1.24 was obtained considering that the vaccine had been administered to every 1-year-old individual at a price of EUR 28.59 per vaccine. Over the 11-year period, 53% of hospitalizations corresponded to children younger than 5 years old. Conclusions. Public campaigns for the immunization of children younger than 4 years old with 2 doses lead to cost savings and are cost-effective because the vaccine price results in a benefit-cost ratio greater than 1. A major reduction is expected in the number of hospitalizations among children aged 3-4 years.

show abstract

“…[1][2][3][4][5]7 Outbreaks in schools have been observed with a single dose and coverage close to 99%. 5 Also with a single dose, the age of varicella onset may be delayed.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

A cost-benefit analysis of varicella vaccination in Aragón

Blasco

Pérez-Aramendía

2017

Arch Argent Pediat

View full text Add to dashboard Cite

show abstract

Evaluation of impact of one dose varicella vaccine on the incidence of chickenpox in Argentina

Barrenechea¹,

Bastos

2020

Vaccine

View full text Add to dashboard Cite

Introduction. Varicella, also known as chickenpox is one of the most common immunizable diseases. In 1998, the World Health Organization (WHO) recommended to incorporate this vaccine in the national immunization programs, which Argentina did in 2015. Objectives. To describe the behavior of the varicella time series for the 2005-2017 period, and to evaluate the impact of the vaccine in Argentina. Methodology. An ecological observational study was performed, using the varicella cases reported in the National Health Monitoring System, and the data of the National census as secondary data sources. A model based time series analysis of the notified varicella cases in Argentina was performed, using a Negative Binomial Mixed Model. For the verification of the vaccine impact, the 2005-2014 period was selected, and a prognosis for the following years was performed. Impact was evaluated by comparing the rates and confidence intervals between the predicted and observed values. Results. Argentina reported 1,775,587 varicella cases for the 2005-2017 period. The series exhibited seasonality, and, a decreasing trend in the number of cases was observed in 2016 and 2017. A reduction of the incidence rate after the implementation of the vaccine was observed. The transmission risk decreased in the country after vaccine implementation. Conclusions. This study is the first concrete evidence of the varicella incidence decline after the implementation of a single dose application program in Argentina.

show abstract

Ofidios y calor estivo: una enmienda necesaria en el texto de Plinio (<em>Nat</em>. XXIX 71)

Ferraces-Rodríguez

2019

Emerita

View full text Add to dashboard Cite

Según Plinio (Nat. XXIX 71) la culebra no es venenosa, pero puede llegar a serlo durante un período de tiempo por influjo de la luna (neque anguis uenenatus est nisi per mensem luna instigatus). La lectura per mensem carece de sentido porque los ofidios permanecen en letargo durante la época invernal. Por tanto, per mensem no puede hacer referencia a un mes cualquiera del año. Un pasaje de Gargilio Marcial y un testigo de la tradición indirecta de la Naturalis Historia apoyan la corrección per messem. De este modo, el pasaje en discusión se hace transparente y la doctrina de Plinio concuerda con la realidad: la culebra se vuelve venenosa en época estival, cuando tiene lugar la siega de la mies (messis).

show abstract

Vacunas frente al virus de la varicela zóster

Cited by 5 publications

References 121 publications

A cost-benefit analysis of varicella vaccination in Aragón

A cost-benefit analysis of varicella vaccination in Aragón

Evaluation of impact of one dose varicella vaccine on the incidence of chickenpox in Argentina

Ofidios y calor estivo: una enmienda necesaria en el texto de Plinio (<em>Nat</em>. XXIX 71)

Contact Info

Product

Resources

About