Validating a point of care lactate meter in adult patients with sepsis presenting to the emergency department of a tertiary care hospital of a low- to middle-income country

Baig, Muhammad Akbar; Shahzad, Hira; Hussain, Erfan; Mian, Afsar

doi:10.5847/wjem.j.1920-8642.2017.03.004

Cited by 19 publications

(7 citation statements)

References 25 publications

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“…9,10 The fingertip POC lactate meter was highly accurate as it has interclass correlation of over 90% at both ED arrival and 6 h after ED arrival. 26 Even though there are several available POC lactate meters, they are comparable and reliable. 27 In conclusion, POC serum lactate level may be associated with mortality in sepsis patients at community hospitals.…”

Section: Discussionmentioning

confidence: 99%

A Point-of-Care Serum Lactate Level and Mortality in Adult Sepsis Patients: A Community Hospital Setting

Charoentanyarak

Sawunyavisuth

Deepai

et al. 2021

J Prim Care Community Health

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Introduction: Sepsis is a serious and emergency condition that may lead to acute circulatory failure associated with infection. Serum lactate level of over 4 mmol/L is associated with sepsis mortality. However, there is limited data on using a point of care (POC) for fingertip lactate level on sepsis mortality in community hospital setting. This study aimed to evaluate roles of POC for serum lactate with combination of clinical factors on mortality prediction in sepsis patients. Methods: This was a retrospective cohort study conducted at 7 community hospitals. The inclusion criteria were adult patients with diagnosis of sepsis who were tested for POC lactate level. Electronic chart reviews of eligible patients were performed. Predictors for mortality were computed using clinical factors and POC lactate level. Results: There were 1641 patients met the study criteria. The mortality rate was 8.96% (147 patients). There were 3 independent factors associated with mortality: age, co-morbid diseases, and POC lactate level. The adjusted odds ratio (95% CI) of POC lactate level was 1.025 (1.002, 1.048). The cut point of serum lactate was 1.6 mmol/L gave sensitivity of 79.59% and specificity of 32.10%. Conclusion: POC serum lactate level may be associated with mortality in sepsis patients at community hospitals. Lactate level of 1.6 mmol/L may be an indicator for mortality with good sensitivity. Physicians may consider more aggressive and prompt management in individuals with sepsis and POC serum lactate of 1.6 mmol/L or over.

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Section: Discussionmentioning

confidence: 99%

A Point-of-Care Serum Lactate Level and Mortality in Adult Sepsis Patients: A Community Hospital Setting

Charoentanyarak

Sawunyavisuth

Deepai

et al. 2021

J Prim Care Community Health

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“…They conclude that capillary lactate levels could be a more sensitive method than the classical lactate measurement for predicting the outcomes of acute conditions, especially infections. Recently, Baig et al 21 examined the accuracy and timesaving effect of a handheld point of care lactate device for the measurement of fingertip and whole blood lactate and compared it with the reference laboratory blood testing in a sample of adult emergency department patients and conclude that fingertip point of care lactate measurement is an accurate method to determine lactate levels in septic adult emergency department patients. On the other hand, no portable device is absolutely accurate for the analysis of serum lactate levels, but it has been estimated that such devices are reliable enough for the determination of serum lactate levels.…”

Section: Discussionmentioning

confidence: 99%

Silicone ring tourniquet versus pneumatic cuff tourniquet in total knee arthroplasty surgery: A randomised comparative study

León‐Muñoz

Lisón-Almagro

Hernández-Garcı́a

et al. 2018

Journal of Orthopaedics

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“…Five-minutes after executing the WU protocols, the running-based anaerobic sprint test (RAST) was performed. Before and after the WU protocols (immediately), before and after the RAST (immediately), blood lactate concentration was assessed using a ngertip blood lactate (Lactate Scout+, Cosmos Sirius, Germany) (ICC=0.93 & 0.95) [30]. and rest heart rate (RHH) and maximum HR (MHR) was measured (Polar Electro Inc., Lake Success, Finland) (ICC >0.99) [31] to follow HR changes from rest to maximal work and to make sure of maximum effort of subjects.…”

Section: Methodsmentioning

confidence: 99%

Does Post-Activation Potentiation Protocols affect Anaerobic Performance in women Taolu Wushu Athletes?

Afonso¹,

Moradian²,

Eslami³

et al. 2021

Preprint

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Introduction: Post-activation potentiation has an influence on short duration and high intensity function. This study aimed to answer this question whether post-activation potentiation protocol in different models has effect on anaerobic performance in women Wushu athletes. Methods: Women elite Taolu Wushu athletes participated in current crossover design study. (i) specific Wushu WU (Wushu WU); (ii) Strength-based WU (StreWU); and (iii) Speed-based WU (SpeWU) were performed by Wushu athletes in three inconsecutive days separated by 48 h. Five minutes after each WU protocols, Running-Based Anaerobic Sprint Test (RAST) was performed. Heart rate, immediately, and blood lactate were measured for 4 times: before WU protocols, immediately after WU protocols, before RAST, immediately after RAST.Results: Data analysis revealed significant differences in 4 time points of lactate levels (p=0.001; d=1.71), although no significant difference among protocols was observed. Values of variables obtained from RAST showed that StreWU had a significant impact on minimum power (p<0.05; d=-0.795) comparing to WushuWU and on fatigue index comparing to SpeWU (p<0.05; d=-0.799). No significant differences were found among the WU protocols for peak power and mean power.Conclusion: All WU protocols had mostly the same effect, and PAP was not very effective. Possibly, the WU protocols generated too much fatigue, due to the short-term rest time. However, longer intervals would likely enter the realm of post-activation performance enhancement, which is distinct from PAP.

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Validating a point of care lactate meter in adult patients with sepsis presenting to the emergency department of a tertiary care hospital of a low- to middle-income country

Cited by 19 publications

References 25 publications

A Point-of-Care Serum Lactate Level and Mortality in Adult Sepsis Patients: A Community Hospital Setting

A Point-of-Care Serum Lactate Level and Mortality in Adult Sepsis Patients: A Community Hospital Setting

Silicone ring tourniquet versus pneumatic cuff tourniquet in total knee arthroplasty surgery: A randomised comparative study

Does Post-Activation Potentiation Protocols affect Anaerobic Performance in women Taolu Wushu Athletes?

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