Valorization of quince peel into functional food ingredients: A path towards “zero waste” and sustainable food systems

Othman, Souha; Añibarro-Ortega, Mikel; Días, María Inês; Ćirić, Ana; Mandim, Filipa; Sokóvić, Marina; Ferreira, Isabel C.F.R.; Pinela, José; Barros, Lillian

doi:10.1016/j.heliyon.2022.e11042

Cited by 16 publications

(31 citation statements)

References 43 publications

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“…Apart from this, the presence of coumaroylquinic acid derivatives, kaempferol 3- O -rutinoside, quercetin-3- O -glucoside, etc., was also described. Furthermore, analogous to our study, In et al in their study reported the presence of catechins, epicatechins, kaempferol, and quercetin in quince hydroethanolic peel extract, which further ascertains the presence of the high-value phytoconstituents of pharmacological importance in the quince peel …”

Section: Resultssupporting

confidence: 90%

“…Moreover, the values in the heat reflux extraction were found to be higher than those in the ultrasonic extraction, which imply that temperature has a notable influence on the polyphenol extraction owing to the weakening of phenolic interactions at higher temperatures that results in the increase in the diffusion rate of phenolics. In et al also confirmed the maximum abstraction of phenols and flavonoids from quince peels in the hydroethanolic extract, describing it as the most suitable solvent for phenolic and flavonoid extraction . Similarly, Alothman et al confirmed that hydroalcoholic extraction can be commonly used for the phenolic extraction from pineapple, banana, and guava due to its ability to dissolve a wide range of phenols .…”

Section: Resultsmentioning

confidence: 92%

“…Among the microminerals, iron (Fe) was found in the highest amount, which is an important constituent of several proteins, such as hemoglobin. In et al also reported the higher predominance of macronutrient potassium and micronutrient iron in the quince peel …”

Section: Resultsmentioning

confidence: 96%

“…In et al also reported the higher predominance of macronutrient potassium and micronutrient iron in the quince peel. 24 2.5. FTIR of the Best Active Extract.…”

Section: Estimation Of Antioxidant Activitymentioning

confidence: 99%

“…Furthermore, analogous to our study, In et al in their study reported the presence of catechins, epicatechins, kaempferol, and quercetin in quince hydroethanolic peel extract, which further ascertains the presence of the high-value phytoconstituents of pharmacological importance in the quince peel. 24 2.8. In Vivo Cardioprotective Studies of the Best Active Extract.…”

Section: Estimation Of Antioxidant Activitymentioning

confidence: 99%

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Utilization of Quince (Cydonia oblonga) Peel and Exploration of Its Metabolite Profiling and Cardioprotective Potential Against Doxorubicin-Induced Cardiotoxicity in Wistar Rats

Hanan,

Hasan,

Zahiruddin

et al. 2023

ACS Omega

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Quince (Cydonia oblonga Mill.) is a pomaceous fruit that is typically processed into jams, jellies, and marmalade. The byproduct, i.e., the quince peel emanated from the processing industry, can be upcycled, ensuring zero waste policy and resulting in a sustainable food system. In our study, the quince peel was explored for in vitro phytochemical analysis and in vivo cardioprotective potential. Two diverse extractions (ultrasonication and reflux) and four different solvents (aqueous, ethanolic, hydroethanolic, and methanolic) were used for the extraction of quince peel and assessed for the phytochemical and antioxidant study. Among all the evaluated extracts, hydroethanolic quince extract extracted through the reflux extraction method showed the maximum phenolic (27.23 ± 0.85 mg GAE/g DW) and flavonoid (16.5 ± 1.02 mg RE/g DW) content. The maximum antioxidant potential (DPPH) with an IC50 value of 204.8 ± 2.24 μg/mL was noted for the hydroethanolic extract. This best active extract was then subjected to HPTLC, UPLC–MS, mineral, and FTIR analysis to study the metabolic profiling and inorganic composition and to confirm the presence of bioactives. Additionally, the in vivo study was done in rats using doxorubicin (DOX)-induced cardiotoxicity. The rats were given extracts orally at 160 and 320 mg/kg bw for 30 days. ECG analysis was done at the termination of the experiment. Besides this, the lipid profile, blood serum parameters (CK-MB, LDH, AST), and tissue parameters (MDA, SOD, GSH, CAT) were analyzed. The DOX-treated group unveiled a substantial variance (p < 0.001) in all the parameters in contrast to the normal control group and extract control groups. However, the pretreated groups substantially alleviated the DOX-induced changes in all the parameters. Additionally, recuperation in histopathological alterations of the cardiac tissue in contrast to the DOX-induced toxicity was also seen in the pretreated groups. Thus, it could be said that the cardioprotective activity of the quince peel extract attributed to the presence of phytoconstituents counteracted the DOX-induced cardiotoxicity and assisted in the restoration of the cardiac injury in rats.

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Section: Resultssupporting

confidence: 90%

Section: Resultsmentioning

confidence: 92%

Section: Resultsmentioning

confidence: 96%

“…In et al also reported the higher predominance of macronutrient potassium and micronutrient iron in the quince peel. 24 2.5. FTIR of the Best Active Extract.…”

Section: Estimation Of Antioxidant Activitymentioning

confidence: 99%

Section: Estimation Of Antioxidant Activitymentioning

confidence: 99%

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