Variants in GH, IGF1, and LEP genes associated with body traits in Santa Inês sheep

Machado, Alessandro Lima; Meira, Ariana Nascimento; Jucá, Adriana de Farias; Azevedo, H. C.; Muniz, E. N.; Coutinho, Luiz Lehmann; Mourão, Gerson Barreto; Pedrosa, Victor Breno; Pinto, L. F. B.

doi:10.1590/1678-992x-2019-0216

Cited by 5 publications

(2 citation statements)

References 37 publications

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“…Awassi ewes' GH gene variant affects lamb BW as well as the WH, RH, and CC between birth and weaning [43]. Furthermore, an SNP on the GH gene intron 2 region (C>A) significantly affects the LW of Santa Ines sheep on the 100th day [44]. GHE5 polymorphism significantly affects RH and CD at weaning (90th day) (Figure S1a).…”

Section: Discussionmentioning

confidence: 99%

Effect of Growth Hormone Exon-5 Polymorphism on Growth Traits, Body Measurements, Slaughter and Carcass Characteristics, and Meat Quality in Meat-Type Lambs in Turkey

Esen¹,

Elmacı

2022

Ruminants

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This study examined the relationship between GHE5 polymorphisms and growth and carcass characteristics of meat-type sheep breeds reared in Turkey. A total of 202 lambs were tested, consisting of five breeds. By SSCP analysis and nucleotide sequencing, 14 nucleotide changes (12 substitutions and two deletions) were identified in four variants of GHE5. In the coding region of GHE5, five substitutions occur, including c.1588C>Y(C/T) (Ala160Val), c.1603A>M(A/C), c.1604G>S(G/C) (Lys165Thr), c.1606A>W(A/T) (Gln166Leu), and c.1664C>Y(C/T). P3 female and P1 male lambs had the highest rump height at weaning, whereas P3 females and P2 males had the highest chest depth (p < 0.05). At yearling, P1 variant lambs have longer body length (BL; p < 0.05), wider leg circumferences, and thinner cannon bone perimeter (CBP) (p > 0.01), in contrast to P2 variant lambs, which have a shorter BL and thicker CBP. Furthermore, P2 had a greater percentage of neck, shoulder, and leg, P1 had a greater percentage of loin, and P3 had a greater percentage of rack, but there was no significant difference between them. A marker-assisted selection approach can be used to improve sheep carcass quality traits by taking advantage of the nucleotide substitutions found on GHE5 and the detected differences between variants.

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Section: Discussionmentioning

confidence: 99%

Effect of Growth Hormone Exon-5 Polymorphism on Growth Traits, Body Measurements, Slaughter and Carcass Characteristics, and Meat Quality in Meat-Type Lambs in Turkey

Esen¹,

Elmacı

2022

Ruminants

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“…Sadeghi et al (2020) also reported that carcass traits were affected by DGAT1 polymorphism in Iranian Zel and Lori-Baktiari sheep breeds. Machado et al (2019) reported GH, IGF1, and LEP gene can be candidate genes for related carcasses because they play vital roles in the metabolism process and growth.…”

Section: Effect Of Dgat1 Gene On Carcass Traitsmentioning

confidence: 99%

Effect of DGAT1 Gene on Hot and Cold Carcass, Neck and Non-Carcass Traits in Indonesia Sheep

Amri

Gunawan

Sumantri

2023

JIPTHP

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Quality carcass and non-carcass are two inseparable components that result from slaughtering animals with high economic value. The aims study is effect of polimorfisme DGAT1 gene on hot and cold carcass, neck and non-carcass traits in Indonesia sheep. A total of 50 rams used in this study were collected from 10 Barbados Cross Sheep (BCS), 10 Compass Agrinac Sheep (CAS), 15 Javanese Thin-Tailed Sheep (JTTS), and 15 Jonggol Sheep (JS). The sheep were slaughtered at 10-12 months old with an average body weight of 20.45 kg. Identification of the DGAT1 gene polymorphism was performed by Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). The effect of the DGAT1 gene and breed with carcass and non-carcass traits were described using a T-test. The result showed that we found two genotypes: CC (466 bp), and CT (76, 390, and 466 bp) in sheep. The DGAT1 gene polymorphisms (g.8539 C>T) were in Hardy-Weinberg Equilibrium (HWE). The DGAT1 gene polymorphisms had a significant (P<0.05) on carcass traits in neck. However, the DGAT1 gene had no significant association (P>0.05) with non-carcass traits. The CT genotype had the highest value of carcass traits compared to CC genotypes. Therefore, the quality of carcass and non-carcass in Indonesian sheep for the DGAT1 gene only affects the neck value.

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Association of single nucleotide polymorphisms in the CAPN, CAST, LEP, GH, and IGF-1 genes with growth parameters and ultrasound characteristics of the Longissimus dorsi muscle in Colombian hair sheep

Lenis-Valencia

Franco

Hernández-Herrera

2022

Trop Anim Health Prod

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Variants in GH, IGF1, and LEP genes associated with body traits in Santa Inês sheep

Cited by 5 publications

References 37 publications

Effect of Growth Hormone Exon-5 Polymorphism on Growth Traits, Body Measurements, Slaughter and Carcass Characteristics, and Meat Quality in Meat-Type Lambs in Turkey

Effect of Growth Hormone Exon-5 Polymorphism on Growth Traits, Body Measurements, Slaughter and Carcass Characteristics, and Meat Quality in Meat-Type Lambs in Turkey

Effect of DGAT1 Gene on Hot and Cold Carcass, Neck and Non-Carcass Traits in Indonesia Sheep

Association of single nucleotide polymorphisms in the CAPN, CAST, LEP, GH, and IGF-1 genes with growth parameters and ultrasound characteristics of the Longissimus dorsi muscle in Colombian hair sheep

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