Variation in the amylase isoenzymes of human parotid saliva in health and disease

Skurk, A; Fritsche, D; Fendel, K

doi:10.1016/0003-9969(75)90229-0

Cited by 6 publications

(1 citation statement)

References 13 publications

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“…As in many previous investigations on salivary flow and amylase activity [Kelsay et al, 1972;Skurk et al, 1975;Blomfield et al, 1976;Schmidt and Gocke, 1976;Mandel and Wotman, 1976;Pangborn and Lundgren, 1977;Skurk et al, 1979] there was a considerable inter subject variability, but good reproducibility of intrasubject salivary parameters: the in teraction of the volunteer's hydrolytic po tential, starch hydrolysis and interdental plaque pH seemed to be consistent for each subject. The form in which the wheat starch substrate was administered had only a limit ed effect (table I).…”

Section: Discussionmentioning

confidence: 78%

Oral Starch Degradation and Its Influence on Acid Production in Human Dental Plaque

Mörmann

Mühlemann²

1981

Caries Res

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Enzymatic hydrolysis of starch by salivary α-amylase, its time dependence and influence on plaque acid production was investigated. Analysis of the composition of starch digests was performed with gel filtration chromatography. Wheat starch in solution, in bread and in biscuit was hydrolyzed rapidly mainly to maltose, maltotriose and limit dextrins. In vivo enzymatic degradation of wheat starch caused marked drops in interdental plaque pH to 4.75 measured by intraoral plaque pH telemetry, most probably as the result of the fermentation of low molecular weight maltodextrins by plaque bacteria. On this basis starch may contribute to cariogenesis.

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