Variation of Phenolic Compounds Contents in Cultivated Astragalus membranaceus

Abstract

: This study was conducted to determine the contents of phenolic compounds and astragalosides in Astragalus membranaceus. Between the phenolic compound groups, flavonoids compounds (51.13%) had higher average concentrations than the phenolic acids groups. Among the 30 phenolic compounds, quercetin (353.11 ㎍ g -1 ) provided the highest concentrations. According to different cultivation year, 3-year-cultivated Astragalus (2612.57 ㎍ g -1 ) showed the highest concentrations of phenolic compounds. According to different harvest days, 6/5 harvesting Astragalus (2615.80 ㎍ g -1 ) showed the highest concentrations of phenolic acids. Comparison between the top and subterranean parts of harvested Astragalus plants cultivated for 2 years, 3 years, and 5 years showed big difference of total phenolic compounds in concentrations. Further, the top part had higher amounts of the total phenolic compounds than the subterranean part among all Astragalus. This tendency was similar to those of the top root and lateral root. The concentration of the phenolic compounds in the top root was higher than that of the lateral root.

Protective effects of a mixed plant extracts derived fromAstragalus membranaceusandLaminaria japonicaon PTU‐induced hypothyroidism and liver damages

“…It, therefore, seems to be need that some other alternative agents, especially natural antioxidants have less toxicities (Kim, Ku, et al, ; Ku & Lee, ). In search of potential active components in AL mix for suppressing hypothyroidism, the FA was identified by RP‐HPLC analysis and estimated as 0.103 mg/g of AL, which corresponds to 3.676 mg/100 g of dried powder, and the result was in agreement with the previous report (Jun et al, ). The iodine content in AL mix was quantified as 263 µg/g of AL.…”

“…The biofunctional activities of AWE and LWE are substantiated by the modern pharmacological research showing that the effects against common cold, fatigue, anorexia, diarrhea (Tin et al, 2006;Tseng et al, 2016), immune disorders (Chao et al, 2017), Ovarian cancer (Zhang et al, 2018), and thyroid cancer (Yeo et al, 2014) and chronic Kidney disease and adrenalin-promoted vascular endothelial damage (Li et al, 2014), respectively. The major bioactive substances of AWE are flavonoids, saponins, and polysaccharides (Ma, Shi, Duan, Dong, & Tsim, 2002), among them, ferulic acid (FA) is reported to be widely present in AWE (Jun et al, 2012), while LWE comprises of large extent of dietary iodine with various trace elements (Zava & Zava, 2011), polysaccharides (Li et al, 2014), and fucoidan (Wang, Wang, Yun, Zhang, & Zhang, 2012).…”

Antiparasitic activity of Astragalus brachycalyx subsp. brachycalyx extract against hydatid cyst protoscoleces and its effect on induction of apoptosis: an in vitro and ex vivo study

“…According to the previous investigations the phenolic and flavonoid compounds are the most frequent phytochemicals of Astragalus spp., while several subclasses of flavonoids, e.g., flavones, flavonols, flavanones, flavanonols, chalcones, aurones, isoflavones, isoflavones, and pterocarpans have been extracted from the genus Astragalus (34,35). In connection with antimicrobial effects of flavonoid phytochemicals, previous reports exhibited that these phytochemicals displayed their antimicrobial action through distracting the function of cytoplasmic membrane, inhibiting nucleic acid synthesis, destructing cell-membrane, triggering apoptosis, disturbing metabolism of energy, stopping the biofilm formation, altering the membrane permeability, and decreasing the pathogenicity (36,37).…”

Comparison of flavonoid contents and antioxidant activities of Vicia species

“…The truffle ( Terfezia boudieri Chatin) contains 0.25 μg/g of naringenin (Akyuz, 2013). The mean concentration of naringenin in cultivated Astragalus membranaceus is 49.0 μg/g (Jun et al , 2012). Our Vicia accessions had high naringenin contents, which accounted for >70% of TFC (Supplementary Table S1, available online).…”