Vasospasms of Cerebral Arteries in Hyperemesis gravidarum

Kanayama, Naohiro; Khatun, Selina; Belayet, Hossain Md; Yamashita, Miwa; Yonezawa, Masumi; Kobayashi, Takao; Terao, Toshihiko

doi:10.1159/000010018

Cited by 12 publications

(8 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Common maternal complications include weight loss, dehydration, micronutrient deficiency, and muscle weakness. More severe, albeit rare, complications include Mallory‐Weiss tears, esophageal rupture, Wernicke's encephalopathy with or without Korsakoff's psychosis, central pontine myelinolysis due to rapid correction of severe hyponatremia, retinal hemorrhage, spontaneous pneumomediastinum, and vasospasm of the cerebral arteries . HG may also lead to psychologic problems and result in termination of an otherwise wanted pregnancy and decreased likelihood to attempt a repeat pregnancy …”

Section: Discussionmentioning

confidence: 99%

Hyperemesis Gravidarum

2018

View full text Add to dashboard Cite

Nausea and vomiting of pregnancy affect the majority of pregnancies, while the most severe version, hyperemesis gravidarum (HG), affects a much smaller subset of women. Despite the prevalence of nausea and vomiting of pregnancy and the severe consequences of HG, the pathophysiology of these conditions is not fully understood. Currently, it is thought that a combination of hormonal factors accounts for their development. Multiple treatments have been described for nausea and vomiting of pregnancy and HG with varying levels of success. In this paper we describe the epidemiology of nausea and vomiting of pregnancy and HG, the recommended workup, their proposed etiologic factors, treatments, and their potential impact on mother and baby.

show abstract

Section: Discussionmentioning

confidence: 99%

Hyperemesis Gravidarum

2018

View full text Add to dashboard Cite

show abstract

“…More severe, albeit rare, complications include Mallory-Weiss tears, esophageal rupture, Wernicke’s encephalopathy with or without Korsakoff’s psychosis, central pontine myelinolysis due to rapid correction of severe hyponatremia, retinal hemorrhage and spontaneous pneumomediastinum [47]. Vasospasm of the cerebral arteries due to increased sympathetic activity has also been reported [115]. …”

Section: Hyperemesis Gravdiarummentioning

confidence: 99%

Nausea and Vomiting of Pregnancy

Lee

Saha

2011

Gastroenterology Clinics of North America

298

215

View full text Add to dashboard Cite

“…Potential mechanisms include 1) sympathetic responses to dehydration that may cause vasospasm within the cerebral vasculature15; 2) defective ion channel processes such as those found in migraineurs16; 3) inflammatory substances that may be produced in women with HG17; and 4) estrogen or other humoral or hormonal factors that may be produced or responded to abnormally by the vestibular system18. Estrogen, for example, has been shown to trigger gastric dysrhythmias, which may themselves trigger the medullary vomiting center19.…”

Section: Commentmentioning

confidence: 99%

The first demonstration that a subset of women with hyperemesis gravidarum has abnormalities in the vestibuloocular reflex pathway

Goodwin¹,

Nwankwo²,

O'Leary³

et al. 2008

American Journal of Obstetrics and Gynecology

View full text Add to dashboard Cite

Objective-The vestibular system is a major pathway to nausea and vomiting, and the vestibuloocular reflex (VOR) is a central component; its function can be studied using the vestibular autorotation test (VAT). We hypothesize that women with hyperemesis gravidarum (HG) may have VOR abnormalities.Study Design-Women with HG were compared to women without HG using the VAT. Horizontal and vertical VOR gains and phases were evaluated at three frequency ranges: low (2.0-3.5 Hz), medium (>3.5 -5.0 Hz), and high (>5.0 -6.0 Hz) during pregnancy and postpartum.Results-Twenty women with HG and 48 unaffected women were evaluated in early pregnancy. Women with HG had higher horizontal gains at all three frequency ranges. Horizontal phase differences were also observed at medium frequencies. No VAT differences were noted postpartum.Conclusions-Women experiencing HG had a higher mean VOR horizontal gain and lower horizontal phase when compared to unaffected women.

show abstract

Vasospasms of Cerebral Arteries in Hyperemesis gravidarum

Cited by 12 publications

References 8 publications

Hyperemesis Gravidarum

Hyperemesis Gravidarum

Nausea and Vomiting of Pregnancy

The first demonstration that a subset of women with hyperemesis gravidarum has abnormalities in the vestibuloocular reflex pathway

Contact Info

Product

Resources

About