Vaterite vectors for the protection, storage and release of silver nanoparticles

Ferreira, Ana M.; Vikulina, Anna S.; Cave, Gareth W. V.; Loughlin, Michael; Puddu, Valeria; Volodkin, Dmitry

doi:10.1016/j.jcis.2022.10.094

Cited by 17 publications

(18 citation statements)

References 65 publications

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“…Whatman filter was punched to make discs (6 mm in diameter) and sterilized by an autoclave for 15 min at 121 °C to obtain sterile discs. 46 with slight modifications. The release of AgNPs in both closed-like and open-like systems was investigated under slightly acidic pH (pH 6, acetate buffer).…”

Section: Thermogravimetric Analysis (Tga) and Differential Scanning C...mentioning

confidence: 99%

Biogenic Vaterite Calcium Carbonate-Silver/Poly(Vinyl Alcohol) Film for Wound Dressing

Azarian,

Junyusen,

Sutapun

2023

ACS Omega

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Vaterite, a spherical polymorph of CaCO 3 , shows potential as a carrier for the stable and controlled release of silver nanoparticles (AgNPs), preventing their aggregation or loss of efficacy during application. Furthermore, the embedding of CaCO 3 − Ag in a poly(vinyl alcohol) (PVA) matrix helps effectively encapsulate and protect the CaCO 3 −Ag microspheres and provides mechanical stability for better contact with the wound surface. This article focuses on the fabrication of an antimicrobial and biocompatible absorbent film embedded with precipitated biogenic vaterite CaCO 3 −Ag microspheres. The impact of vaterite CaCO 3 −Ag on the physical, chemical, nanomechanical, biocompatibility, and antimicrobial properties of the PVA films was investigated. The morphology study revealed a bilayer film structure with an inactive and active surface containing homogeneously distributed vaterite CaCO 3 −Ag. The X-ray photoelectron spectroscopy (XPS) analysis of the spin−orbit splitting in the Ag 3d 5/2 and Ag 3d 3/2 peaks indicated the presence of both metallic and ionic states of silver in vaterite CaCO 3 −Ag prior to its incorporation into the PVA polymer matrix. However, upon embedding in the PVA matrix, a subsequent transformation to solely ionic states was observed. The nanomechanical properties of PVA improved, and the reduced modulus and hardness increased to 14.62 ± 5.23 and 0.64 ± 0.29 GPa, respectively. The films demonstrate a significant activity toward Gram-negative Escherichia coli bacteria. The release of AgNPs was studied in both open and closed systems at pH 6, mimicking the pH environment of the wound, and it demonstrated a dependency on the type of capping agent used for synthesis and loading of AgNPs. The results further revealed the biocompatibility of the prepared films with human dermal fibroblast cells at a concentration of ≤5 mg/mL, making them applicable and functional for wound dressing applications.

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Section: Thermogravimetric Analysis (Tga) and Differential Scanning C...mentioning

confidence: 99%

Biogenic Vaterite Calcium Carbonate-Silver/Poly(Vinyl Alcohol) Film for Wound Dressing

Azarian,

Junyusen,

Sutapun

2023

ACS Omega

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“…Table 1 presents the zeta potential of the AgNPs in Milli-Q water which is consistent with our previous study. 26 All the nanoparticles, except for the AgNPs-Dex DEAE , had a negative zeta potential (−21.9 to −36.4 mV) which is due to the polyanionic nature of some of the capping agents, i.e., citrate ions and Dex CM , and the presence of electrons on the surface of metallic nanoparticles which are sufficient to endow a negative charge due to the low mass of the AgNPs. 27,28 The AgNPs coated with Dex DEAE , were the only nanoparticles that presented a positive potential (ca.…”

Section: Resultsmentioning

confidence: 99%

How similar is the antibacterial activity of silver nanoparticles coated with different capping agents?

et al. 2023

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“…This includes factors such as the extent of silver ion release, the nature of interactions, and the ability of nanoparticles to permeate through biological barriers. 70 For instance, at a concentration of 500 mg mL À1 , fatty acidcapped AgNPs of size B6nm inhibited P. aeruginosa and S. aureus biofilm formation by B75% and B55%, respectively, whereas 100 mg mL À1 of chitosan-stabilized AgNPs with a size of 22 nm had a biofilm inhibition efficiency of 65% and 75% against methicillin-resistant S. aureus and P. aeruginosa, respectively. 71,72 In this context, the obtained nanocomposites have shown significant potency in terms of both biofilm inhibition and eradication.…”

Section: Discussionmentioning

confidence: 99%

Comparative analysis of the physicochemical and anti-biofilm properties of iota and lambda carrageenan-capped silver nanocomposites synthesized using response surface methodology

Singh¹,

Pathak²,

Poluri³

2023

New J. Chem.

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Vaterite vectors for the protection, storage and release of silver nanoparticles

Cited by 17 publications

References 65 publications

Biogenic Vaterite Calcium Carbonate-Silver/Poly(Vinyl Alcohol) Film for Wound Dressing

Biogenic Vaterite Calcium Carbonate-Silver/Poly(Vinyl Alcohol) Film for Wound Dressing

How similar is the antibacterial activity of silver nanoparticles coated with different capping agents?

Comparative analysis of the physicochemical and anti-biofilm properties of iota and lambda carrageenan-capped silver nanocomposites synthesized using response surface methodology

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