To understand the dynamics of aerosols and their associated influence on regional and global climatic conditions requires the knowledge of spatial and temporal distributions of aerosols on regional and global scales. In this study, the satellite-based MODIS AODs retrievals level 2 products from Terra (MOD04-10 km) and Aqua (MYD04-10 km) satellites were inter-compared with the ground-based AERONET AODs (level 2) over Nghia Do station located in an urban area of Hanoi city, Vietnam for the period of 2010-2016. The Terra AODs showed good-match with the ground-based AODs measurements (slope = 0.830, intercept = 0.099, RMSE = 0.260, R 2 = 0.673, and RMB = 0.970). However, the Aqua AODs expressed systematically the underestimation of AERONET AODs (slope = 0.556, intercept = 0.184, RMSE = 0.390, R 2 = 0.408, and RMB = 0.810). All MODIS AODs indicated the moderate correlation with AERONET AODs (slope = 0.683, intercept = 0.147, RMSE = 0.330, R 2 = 0.520, and RMB = 0.890). Although MODIS AODs followed well the monthly variations of AERONET AODs, the relatively high discrepancy between MODIS and AERONET AODs could be observed during the winter months.