Venous pCO2 and pH can be used to screen for significant hypercarbia in emergency patients with acute respiratory disease

Agreement between Central Venous and Arterial Blood Gas Measurements in the Intensive Care Unit

“…Previous literature showed a mean arterial minus venous difference for Pco 2 ranging from Ϫ6.6 to Ϫ3.0 (4 -6,14,15). Comparing the results of our study with other studies that also reported 95% limits of agreement, the arterial and central venous values for Pco 2 in our study showed better agreement than the study by Kelly et al (5), which demonstrated a mean arterial minus venous difference of Ϫ5.8 with a 95% limits of agreement of Ϫ8.8 to 20.5; however, there was less agreement in our study compared with studies by Malinoski et al (4), which showed a mean arterial minus venous difference of Ϫ4.36 with a 95% limits of agreement of Ϫ2.20 to 10.90 and Malatesha et al (15), which revealed a mean arterial minus venous difference of Ϫ3.0 with a 95% limits of agreement of Ϫ7.6 to 6.8. Overall, the results of our study in regard to Pco 2 are consistent with the existing literature.…”

Prediction of Arterial Blood Gas Values from Venous Blood Gas Values in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

“…However, there are also contradictory reports (Klingstrom et al 1976;Brashear et al 1979). One of these studies was carried out in subjects with respiratory disease (Kelly et al 2002), but none has specifically investigated the population of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in the emergency department. The determination of arterial blood gas values is considered essential in the emergency department evaluation of patients with AECOPD.…”

Effects of Mean Arterial Pressure and Needle Size on Arterial Sampler Filling Time

“…2 Although the pH and bicarbonate of venous blood have been shown to correlate well with the pH and bicarbonate of arterial blood, and may be used to identify patients with extreme hypercarbia, an arterial blood sample is necessary for assessing oxygenation and monitoring ventilation. [7][8][9] Although clinical practice guidelines suggest that blood color and pulsatile blood flow can verify a successful arterial puncture, those are subjective indicators, whereas sampler filling time is an objective indicator and may be more reliable in clinical practice. Lower blood pressures increased sampler filling times, and the longest average filling time was 20.5 s with a mean arterial pressure of 57 mm Hg.…”