Vergleichende Untersuchungen über das Verhalten der Nierenfunktion bei Hochverdünnungsperfusionen mit Glucose, Hämaccel® und Rheomacrodex®

Trede, M.; Róth, E; Encke, A.; Hallwachs, O.; Wänke, Michaela; Stöhrer, F.

doi:10.1007/bf02433695

Cited by 4 publications

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“…TREDE [1454] observed a damaging influence with massive overdosage (more than 6 g/kg bw) in dogs. An improvement of renal perfusion and a rise in oxygen supply [112] seem now confirmed, after infusion of dextran 40 and dextran 75 [131,402,790,194,830,958,961, 1251, 1340, 1839, 1840].…”

Section: ])mentioning

confidence: 98%

Blood Replacement

Gruber¹

1969

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All rights reserved. No part of this book may be translated or reproduced in any form withoutwritten permission from Springer-Verlag. © by Springer-Verlag Berlin Heidelberg 1969. Library of Congress Catalog Card Number 69-16845Softcover reprint of the hardcover 1st edition 1969The use of general descriptive names, trade marks, etc. in this publication, even if the former are not especially identified, is not be taken as a sign that such names, as understood by the Trade Marks and Merchandise Act, may accordingly be used freely by anyone. Title-No. 1551 Dedicated to my wife LisaEs wurde fertig in Deiner Hut. Bleib Du mir auf dieser Erden, so 5011 alles fertig werden. THOMAS MANN ForewordThe manifold problems of shock are still of great importance, diagnostic and therapeutic experience of the "severely ill" being supplied with new information almost every month. In the 5 periodicals which have found their way to my desk during the past few days there are no less than 10 interesting articles on questions concerning shock research [see Bibliography 41 b, 53 a, 60 a, 192 a, 242 a, 350 b, 810 a, 941 a, 1069 a, 1082 a]. The most urgent point still is to maintain as complete as possible the objective catalog of the various shock manifestations found in man and in animals -yet at the same time to view interpretations of these phenomena in their relative and temporal "truth".Problems of shock research are not only interesting for their scientific value but also for their clinical implication. In particular, almost every practicing physician is facing problems of blood replacement very frequently. The effective or circulating blood volume remains an important theoretical and therapeutic problem in the shock field. For years, U. F. GRUBER has pursued this question clinically and experimentally. This volume deals with the world literature in an exceptionally thorough manner. This book is made more than a compilation by including a long list of original work done with F. D. MOORE in Boston, in the Surgical Department in Chur, with L. E. GELIN and S. E. BERGENTZ in Goteborg and in the Laboratory for Experimental Surgery in Davos; judgements are made on the basis of original studies, and essential points are separated from unimportant ones. This volume will be welcomed by the medical profession because it carefully treats vital questions concerning this complicated, much-discussed, and in part contested field, considering that today, along with various forms of blood and several plasma preparations, there are more than 40 different plasma replacement substances available with various physico-chemical, biological and pharmacological properties. Older preparations have been abandoned, others modified, and new ones appear.A comparative evaluation of the chemical characteristics, the range of indication and the therapeutic effectiveness of these solutions suggests itself particularly at this time because in recent years the use of large amounts of balanced electrolyte solutions tended to reverse the principles of blood replaceme...

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Section: ])mentioning

confidence: 98%

Blood Replacement

Gruber¹

1969

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“…The deviation of the various para meters of kidney function (clearances and U/P0Sm) from the control values is less marked than with infusion of clinical or low molecular weight dextran [85]. The exchange of half the normal blood volume with gelatin preparations [93,211], even if aggravated by the addi tional stress of extracorporeal perfusion [211], does not cause renal damage. Nor does the infusion of gelatins in amounts equalling the total normal blood volume as an emergency treatment of large blood losses in man [212,213].…”

Section: Products Division Travenol Laboratories Internationmentioning

confidence: 91%

“…The tubular epithelium and the capillary coils of the glomeruli are compressed [93,118,128,129,211,221]. Alternatively, pro nounced degrees of 'osmotic nephrosis' may be present and cause tubular obstruction by the resulting cellular swelling [59,149].…”

Section: Products Division Travenol Laboratories Internationmentioning

confidence: 99%

“…The infusion of large amounts of low molecular dextran slows down the glomerular filtration rate [155]. Under standardized experimental conditions, the infusion of large doses of low molecular weight dextran combined with renal 'stress' in the form of hemorrhagic shock [85,127] extracorporeal perfusion [97,211] or unilateral renal artery stenosis [128,129] induce oliguric or anurie renal failure. Renal damage consecutive to experimental endotoxin shock may be ag gravated by low molecular weight dextran [222].…”

Section: Products Division Travenol Laboratories Internationmentioning

confidence: 99%

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