Very long-term durability of the edge-to-edge repair for isolated anterior mitral leaflet prolapse: Up to 21 years of clinical and echocardiographic results

Bonis, Michele De; Lapenna, Elisabetta; Taramasso, Maurizio; Canna, Giovanni La; Buzzatti, Nicola; Pappalardo, Federico; Alfieri, Ottavio

doi:10.1016/j.jtcvs.2014.03.041

Cited by 48 publications

(17 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, combined repair techniques increase the mTMG, especially when the edge-toedge technique is used. 12,13) In this study, despite efforts to maintain as large a remnant orifice area as possible, an elevated mTMG was detected in six patients who had undergone edge-to-edge suturing. Considering the fact that removal of the suture would again lead to significant regurgitation, replacement of the mitral valve was performed.…”

Section: )mentioning

confidence: 62%

Management of Incomplete Initial Repair in the Treatment of Degenerative Mitral Insufficiency

Shi

Zhang

et al. 2018

Int. Heart J.

View full text Add to dashboard Cite

SummaryWe sought to present our institutional protocol to manage incomplete initial repair of degenerative mitral regurgitation and to evaluate its mid-term outcomes. Eight hundred and fifteen patients with degenerative mitral insufficiency undergoing mitral valve repair were investigated in this study. The initial repair attempt was incomplete in 48 patients, leaving a degree of residual regurgitation > mild, and an elevated transmitral gradient or systolic anterior motion (SAM). These patients were further treated with medication or mitral valve re-repair or replacement under reinstituted cardiopulmonary bypass. Transesophageal echocardiographic reports and operational records were reviewed to identify morphological causes and establish management of incomplete initial repair. Mid-term outcomes of patients with re-repair and complete initial repair were evaluated and compared. Residual mitral regurgitation > mild was detected in 25 patients, an elevated transmitral gradient was detected in seven patients, and SAM was detected in 16 patients. The condition of eight patients with SAM was resolved with medication only. Mitral valve re-repair was performed in 23 patients and replacement was performed in 17, with comparable early mortality and morbidity. At 60.3 ± 25.5 months after surgery, late mitral stenosis and reoperation rate were significantly higher in re-repair patients than in patients with complete initial repair, despite comparable survival, left chamber reverse remodeling, and degree of residual regurgitation. Based on our institutional protocol, acceptable outcomes can be achieved for patients with incomplete initial mitral valve repair. Management should be tailored based on the characteristics of the mitral valve complex, expected repair durability, and operative risk.(Int Heart J Advance Publication)

show abstract

Section: )mentioning

confidence: 62%

Management of Incomplete Initial Repair in the Treatment of Degenerative Mitral Insufficiency

Shi

Zhang

et al. 2018

Int. Heart J.

View full text Add to dashboard Cite

show abstract

“…The double‐orifice edge‐to‐edge technique has also been associated with a low incidence of IE. De Bonis et al reported, in a series including 139 patients, an incidence of IE of 0.7% after a mean follow‐up of 11.5 years. Hence, IE is an uncommon but life‐threatening complication following surgical mitral valve repair, with high in‐hospital (4%–11%) and 1‐year (26%) mortality rates .…”

Section: Discussionmentioning

confidence: 99%

“…The double-orifice edge-to-edge technique has also been associated with a low incidence of IE. De Bonis et al [22] reported, in a series including 139 patients, an incidence of…”

Section: Management and Outcomes Of Ie Episodesmentioning

confidence: 97%

Infective endocarditis following transcatheter edge‐to‐edge mitral valve repair: A systematic review

Asmarats

Rodríguez‐Gabella

Chamandi

et al. 2018

Cathet Cardio Intervent

View full text Add to dashboard Cite

show abstract

“…In the early 1990s, Alfieri introduced edge-to-edge surgical repair for mitral regurgitation, which involves suturing the free edges of the anterior and posterior mitral leaflets together at the A2-P2 scallops, creating a double mitral orifice and reestablishing leaflet coaptation [11]. The technique has been refined and now routinely includes an annuloplasty ring.…”

Section: From Surgical To Percutaneous Edge-to-edge Repairmentioning

confidence: 99%

Mitral clip–looking back and moving forward

Fam

Ross

Verma

2016

Current Opinion in Cardiology

View full text Add to dashboard Cite

show abstract

Very long-term durability of the edge-to-edge repair for isolated anterior mitral leaflet prolapse: Up to 21 years of clinical and echocardiographic results

Abstract: In patients with MR due to segmental anterior leaflet prolapse, the very long-term results of the edge-to-edge repair combined with annuloplasty were excellent.

Cited by 48 publications

References 23 publications

Management of Incomplete Initial Repair in the Treatment of Degenerative Mitral Insufficiency

Management of Incomplete Initial Repair in the Treatment of Degenerative Mitral Insufficiency

Infective endocarditis following transcatheter edge‐to‐edge mitral valve repair: A systematic review

Mitral clip–looking back and moving forward

Contact Info

Product

Resources

About