VHP-Female full-body human CAD model for cross-platform FEM simulations — Recent development and validations

Tankaria, Harshal; Jackson, Xavier; Borwankar, Raunak; Srichandhru, Goutham N. K.; Tran, Anh Le; Yanamadala, Janakinadh; Noetscher, Gregory M.; Nazarian, Ara; Louie, Sara; Makarov, Sergey N.

doi:10.1109/embc.2016.7591173

Cited by 15 publications

(13 citation statements)

References 8 publications

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“…SAR and device performance estimates are typically derived and accepted today from computational electromagnetics (CEM) simulations performed with detailed virtual humans [97]. In this study, we use the multi-tissue CEM phantom VHP-Female v. 5.0 (female/60 year/162 cm/88 kg, obese) [97][98][99][100][101][102][103] derived from the cryosection dataset archived within the Visible Human Project® of the US National Library of Medicine [104]. The phantom includes about 250 individual tissues and is augmented with material property values from the IT'IS database [105].…”

Section: Methods Of Analysismentioning

confidence: 99%

Design and Analysis of a Whole-Body Noncontact Electromagnetic Subthreshold Stimulation Device with Field Modulation Targeting Nonspecific Neuropathic Pain

Makarov

Bogdanov

Noetscher

et al. 2019

Brain and Human Body Modeling

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Section: Methods Of Analysismentioning

confidence: 99%

Design and Analysis of a Whole-Body Noncontact Electromagnetic Subthreshold Stimulation Device with Field Modulation Targeting Nonspecific Neuropathic Pain

Makarov

Bogdanov

Noetscher

et al. 2019

Brain and Human Body Modeling

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“…SAR and device performance estimates are typically derived and accepted today from Computational Electromagnetics (CEM) simulations performed with detailed virtual humans [23]. In this study, we use the multi-tissue CEM phantom VHP-Female v. 5.0 (female/60 year/162 cm/88 kg, obese) [23,24], derived from the cryosection dataset archived within the Visible Human Project® of the US National Library of Medicine. The phantom includes about 250 individual tissues and is augmented with material property values from the IT'IS database [25].…”

Section: A Methods Of Analysismentioning

confidence: 99%

Design and Analysis of a Whole Body Non-Contact Electromagnetic Stimulation Device with Field Modulation

Bogdanov

et al. 2018

Preprint

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This study describes a whole-body, non-contact electromagnetic stimulation device based on the concept of a conventional MRI Radio Frequency (RF) resonating coil, but at a much lower resonant frequency (100-150 kHz), with a field modulation option (0.5-100 Hz) and with an input power of up to 3 kW. Its unique features include a high electric field level within the biological tissue due to the resonance effect and a low power dissipation level, or a low Specific Absorption Rate (SAR), in the body itself. Because of its large resonator volume together with non-contact coupling, the subject may be located anywhere within the coil over a longer period at moderate and safe electric field levels. The electric field effect does not depend on body position within the resonator. However, field penetration is deep anywhere within the body, including the extremities where muscles, bones, and peripheral tissues are mostly affected. A potential clinical application of this device is treatment of chronic pain. Substantial attention is paid to device safety; this includes both AC power safety and exposure of human subjects to electromagnetic fields. In the former case, we employ inductive coupling which eliminates a direct current path from AC power to the coil. Our design enhances overall device safety at any power level, even when operated under higher-power conditions. Human exposure to electromagnetic fields within the coil is evaluated by performing modeling with two independent numerical methods and with an anatomically realistic multi-tissue human phantom. We show that SAR levels within the body correspond to International Electrotechnical Commission (IEC) safety standards when the input power level of the amplifier driver does not exceed 3 kW. We also show that electric field levels generally comply with International Commission on Non-Ionizing Radiation Protection safety standards if the input power level does not exceed 1.5 kW.

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“…It was constructed from the photographic cryosection data of the Visible Human Project of the US National Library of Medicine with the world-best isotropic resolution of 0.33 mm. Its construction has been well documented in the literature [5][6][7][8][9][10], but several points are worth emphasizing here:…”

Section: Vhp Female V 50 Anatomical Human Model (Doi 1020298/vhp-fema...mentioning

confidence: 99%

“…

This tool partially described in Refs. [1][2][3][4] is a non-clinical assessment model used to predict the RF power deposition induced temperature rise near orthopedic implants as a function of implant geometry, location, material, and scan time. It is using the complete in silico multiphysics MRI environment and the anatomical human CAD model.

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mentioning

confidence: 99%

Computational Tool Comprising Visible Human Project® Based Anatomical Female CAD Model and Ansys HFSS/Mechanical® FEM Software for Temperature Rise Prediction Near an Orthopedic Femoral Nail Implant During a 1.5 T MRI Scan

Noetscher

Serano

Nazarian

et al. 2022

Brain and Human Body Modelling 2021

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This medical device development tool (MDDT) is categorized as a non-clinical assessment model (NAM). This MDDT is a computational modeling and simulation tool. It can predict heating of metallic orthopedic implants with the radio frequency (RF) electromagnetic fields in the magnetic resonance imaging (MRI) coils while targeting a mid-aged and elderly female population primarily affected by osteoporosis and the associated bone fracture.This MDDT uses a high resolution anatomical female CAD (computer aided design) model coupled with the proven multiphysics finite element method (FEM) software (Ansys Workbench) to simulate the complete MRI environment. The environment is consisting of a tuned MRI coil with the given output power, detailed heterogeneous human model within the coil at the given landmark and a properly embedded metallic implant within the anatomical model to compute the extent of heating generated around the implant.Specifically, this MDDT is the in silico analog of an MRI scan for an elderly female subject with a metallic orthopedic implant at 1.5 T in a full-body birdcage RF coil.

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VHP-Female full-body human CAD model for cross-platform FEM simulations — Recent development and validations

Cited by 15 publications

References 8 publications

Design and Analysis of a Whole-Body Noncontact Electromagnetic Subthreshold Stimulation Device with Field Modulation Targeting Nonspecific Neuropathic Pain

Design and Analysis of a Whole-Body Noncontact Electromagnetic Subthreshold Stimulation Device with Field Modulation Targeting Nonspecific Neuropathic Pain

Design and Analysis of a Whole Body Non-Contact Electromagnetic Stimulation Device with Field Modulation

Computational Tool Comprising Visible Human Project® Based Anatomical Female CAD Model and Ansys HFSS/Mechanical® FEM Software for Temperature Rise Prediction Near an Orthopedic Femoral Nail Implant During a 1.5 T MRI Scan

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