Motion sickness varies across observers. While some experience immediate and severe symptoms, others seem relatively immune. Multiple explanations have been advanced. Some argue that conflicting cues provided by the visual and vestibular systems are the underlying cause. Others claim postural sway, which differs between the sexes, can explain previouslyreported motion sickness susceptibility differences. We used virtual reality to test these accounts.We found that an observer's visual sensitivity to motion parallax predicted susceptibility, but found little evidence for differences based on sex (N = 95; 59 females, 36 males). Furthermore, our results suggest that sex differences are likely due to poor personalization of VR displays, which default to male settings and introduce cue conflicts for the majority of females. These results suggest that the probability of detecting cue conflicts is limited by an observer's sensitivity to specific sensory cues and thus identify a cause for differences in motion sickness severity.