Virus del papiloma humano en cáncer de pulmón no microcítico. Impacto de mutaciones del EGFR o respuesta a erlotinib

Marquez-Medina, Diego; Gasol-Cudós, Ariadna; Taberner-Bonastre, M. Teresa; Pérez-Vargas, Juan Carlos Samamé; Salud, Antonieta; Llombart-Cussac, Antonio

doi:10.1016/j.arbres.2012.04.003

Cited by 5 publications

(2 citation statements)

References 15 publications

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“…In 1998 Flieder [6][7][8] described solitary papilloma in the respiratory system as a rare benign lesion, accounting for less than 0.5% of all tumors in this location. But even more exceptional is its peripheral location in the lung parenchyma.…”

Section: Discussionmentioning

confidence: 99%

“…The squamous type is the most frequent one and its potential for malignancy ranges from 8% to 40% of cases according to the series [9], being enhanced by the carcinogenic effect of tobacco and HPV 16 and 18 serotypes [10]. Back in 1979, Syrjanen [7] described that HPV was associated with non-small cell lung cancer (NSCLC), but it was not until 2003 that Márquez Medina [8] refers for the first time to the possibility that HPV infection is more frequent in patients with an EGFR mutation and sensitivity to erlotinib. Glandular subtype generally affects older patients, without association to tobacco, usually found in peripheral location and no malignant transformation has been described [5].…”

Section: Discussionmentioning

confidence: 99%

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Mixed Solitary Papilloma Presenting as a Cavitary Lung Lesion

María¹,

Giovanna

Matilde

et al. 2021

BJSTR

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Mixed Solitary Papilloma Presenting as a Cavitary Lung Lesion

María¹,

Giovanna

Matilde

et al. 2021

BJSTR

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Human papillomavirus and non‐small cell lung cancer

et al. 2013

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Lung cancer is the most common cause of cancer-related deaths in the world, causing more than one million deaths worldwide each year. Human papillomavirus (HPV) are small non-enveloped DNA viruses that infect squamous epithelial cells. Relevant studies have reported lung cancer-related HPV infection rates that fluctuate between 10% and 80%, depending on the various research methods and geographical factors. Various scholars gathered statistics from global research reports and found that 22.4% of the patients with lung cancer presented with an HPV infection, which suggested that HPV infection may relate to the tumorigenesis of nonsmall cell lung cancer. This article will review the history and discovery of HPV, the correlation between HPV and lung cancer development, and carcinogenesis caused by HPV regulatory genes, such as p53, p21, p16INK4a, and genes related to hypermethylation and genome instability in lung cancer patients with HPV infection. In addition, because studies have highlighted the difference in clinical prognosis for HPV-positive and HPV-negative patients, articles demonstrating the correlation between HPV infection and prognosis for lung cancer patients will be reviewed.

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<p>Possible Oncogenic Viruses Associated with Lung Cancer</p>

Ren

et al. 2020

OTT

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Lung cancer is the most common cause of cancer death worldwide. Tobacco smoking is the most predominant etiology for lung cancer. However, only a small percentage of heavy smokers develop lung cancer, which suggests that other cofactors are required for lung carcinogenesis. Viruses have been central to modern cancer research and provide profound insights into cancer causes. Nevertheless, the role of virus in lung cancer is still unclear. In this article, we reviewed the possible oncogenic viruses associated with lung cancer.

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Virus del papiloma humano en cáncer de pulmón no microcítico. Impacto de mutaciones del EGFR o respuesta a erlotinib

Cited by 5 publications

References 15 publications

Mixed Solitary Papilloma Presenting as a Cavitary Lung Lesion

Mixed Solitary Papilloma Presenting as a Cavitary Lung Lesion

Human papillomavirus and non‐small cell lung cancer

<p>Possible Oncogenic Viruses Associated with Lung Cancer</p>

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