Visual Acuity Improvement in Continuous vs Divided Occlusion in Anisometropic Amblyopia

Irfani, Irawati; Feriyanto, Feri; Oktarima, Primawita; Kartasasmita, Arief

doi:10.2174/1874364101812010001

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…However, in many studies, PTO has been shown to be effective treatment for moderate as well as severe amblyopia. In study by Irfani I and colleagues, half time occlusion was compared to divided half time occlusion, with results being comparable in both groups 13. In another study, the results were similar in FTO and PTO group, but compliance was seen better in children in FTO group.…”

Section: Discussionmentioning

confidence: 96%

Full time occlusion VS part time occlusion in treatment of monocular amblyopia

Mehboob

Shoaib²,

Farooq

2019

Pak J Med Sci

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Objective:To compare improvement in Best Corrected Visual Acuity (BCVA) by Full Time Occlusion (FTO) or Part Time Occlusion (PTO) technique in children with monocular amblyopia.Methods:This randomized control trial was conducted at Combined Military Hospital, Gujranwala from April 2018 to June 2019. A total of 52 children, diagnosed with non-pathological ametropic amblyopia were randomly divided in two groups. Both underwent cycloplegic refraction and assessment of BCVA. Group A underwent FTO for eight weeks with patch removal only during sleep. Group B underwent PTO for 8 weeks with patching done for six hours a day, out of which 1-2 hours were utilized in near work. Final BCVA was checked at eight weeks, and compared between two groups.Results:Mean age of study population was 11.06±3.30 years. Mean BCVA before amblyopia treatment was 0.70±0.20 logMAR, and mean BCVA after eight weeks of amblyopia treatment in both groups was 0.29±0.18 logMAR. Difference in BCVA between both groups was statistically significant (p= 0.023). Mean improvement in lines on Snellen’s Visual acuity chart was 1.92±1.35 lines. In our study, 92% of children in FTO group and 66.6% of children in PTO group achieved BCVA of 6/12 or better.Conclusions:Full time occlusion in children with monocular amblyopia results in greater improvement in BCVA as compared to part time occlusion of six hours per day.

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Section: Discussionmentioning

confidence: 96%

Full time occlusion VS part time occlusion in treatment of monocular amblyopia

Mehboob

Shoaib²,

Farooq

2019

Pak J Med Sci

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Occlusion for stimulus deprivation amblyopia

Antonio-Santos

Vedula

Hatt

et al. 2020

Cochrane Database of Systematic Reviews

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Background-Stimulus deprivation amblyopia (SDA) develops due to an obstruction to the passage of light secondary to a condition such as cataract. The obstruction prevents formation of a clear image on the retina. SDA can be resistant to treatment, leading to poor visual prognosis. SDA probably constitutes less than 3% of all amblyopia cases, although precise estimates of prevalence are unknown. In developed countries, most patients present under the age of one year; in less developed parts of the world patients are likely to be older at the time of presentation. The mainstay of treatment is removal of the cataract and then occlusion of the better-seeing eye, but regimens vary, can be difficult to execute, and traditionally are believed to lead to disappointing results. Objectives-Our objective was to evaluate the effectiveness of occlusion therapy for SDA in an attempt to establish realistic treatment outcomes. Where data were available, we also planned to examine evidence of any dose response effect and to assess the effect of the duration, severity, and causative factor on the size and direction of the treatment effect.

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Comparison of the outcome of partial time occlusion therapy in strabismic versus anisometropic moderate amblyopes

Fawzy

Hamdi

Galal

et al. 2022

Journal of the Egyptian Ophthalmological Society

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Background Early in life, selective visual input disruption to one eye compromises most of the visual aspects, resulting in amblyopia, with a great social and economic effect. Despite being the easiest and most popular treatment regimen, monocular occlusion therapy is often questioned for efficacy in controlling visual abnormalities other than acuity in different etiologies of amblyopia. Purpose To find out the difference in response of moderately amblyopic, anisometropic versus strabismic eyes to partial occlusion therapy regarding visual acuity (VA), contrast sensitivity (CS), and depth of vision and find out any correlation of improvement of these parameters. Patients and methods This prospective comparative study included 49 moderately amblyopic children between 7 and 12 years of age divided into two groups: 25 anisometropic and 24 strabismic ones. Patients received 2-h parent-monitored occlusion regimen with near activity for 6 months on a monthly basis of follow-up. VA, CS, and stereoacuity were evaluated at each visit. Results Both groups showed significant improvement in VA, although the difference in the average amount of improvement was not significant (P<0.0001). Intragroup distribution of improvement was considerably different, where 9% of strabismic amblyopes achieved full visual recovery as compared with 40% of the anisometropic, and 62.5% had residual amblyopia versus 36% in the anisometropic group. CS improved significantly more in the anisometropic group (P=0.0493). Only 42% of the strabismic amblyopes improved in stereoacuity as compared with 88% of the anisometropic ones; the mean difference was not significant. In anisometropic amblyopes, initial VA correlated significantly with CS (P=0.019) and stereoacuity improvement (P=0.0133). Conclusion Moderately amblyopic anisometropic or strabismic children 7–12 years old can get benefit in different visual aspects from part-time occlusion therapy. The anisometropic amblyopes show better CS improvement and more reliable expectations of recovery that are largely dependent on the initial visual.

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Visual Acuity Improvement in Continuous vs Divided Occlusion in Anisometropic Amblyopia

Cited by 3 publications

References 9 publications

Full time occlusion VS part time occlusion in treatment of monocular amblyopia

Full time occlusion VS part time occlusion in treatment of monocular amblyopia

Occlusion for stimulus deprivation amblyopia

Comparison of the outcome of partial time occlusion therapy in strabismic versus anisometropic moderate amblyopes

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