Vitamin D measurement standardization: The way out of the chaos

EAACI position paper: Influence of dietary fatty acids on asthma, food allergy, and atopic dermatitis

“…Also, a small study on DHA supplementation showed a reduction in AD severity in adults after 8 weeks . An open‐label small trial with children and adults showed improvement in SCORAD scores following LC‐PUFA supplementation . However, other RCTs using fish oil in adults and children did not show any benefit over placebo for AD .…”

Vitamin D insufficiency, hemoglobin, and anemia in children with chronic kidney disease

“…However, we acknowledge the lack of consensus in the research community regarding the definition of 25OHD insufficiency, due in part to the substantial variability among available vitamin D assays and a lack of standardization of research data [24]. The Institute of Medicine for example defines 25OHD levels of >20 ng/mL as being sufficient [24].…”

“…However, we acknowledge the lack of consensus in the research community regarding the definition of 25OHD insufficiency, due in part to the substantial variability among available vitamin D assays and a lack of standardization of research data [24]. The Institute of Medicine for example defines 25OHD levels of >20 ng/mL as being sufficient [24]. Therefore we performed an additional regression analysis using a threshold of 20 ng/mL to define 25OHD insufficiency, but there was no significant association between odds of anemia and 25OHD levels below vs. above a threshold of 20 ng/mL.…”

The Use of Vitamins and Minerals in Skeletal Health: American Association of Clinical Endocrinologists and the American College of Endocrinology Position Statement

“…For example, a 25(OH)D laboratory result of 30 ng/mL meeting the 10% CV VDSP recommendation means that the "true" value is between 24 and 36 ng/mL (55). Such variability in 25(OH)D results represents a major challenge to meta-analyses of RCTs (56).…”