Vitamin E improves learning performance and changes the expression of nitric oxide-producing neurons in the brains of diabetic rats

The effects of the Chinese medicine ZiBu PiYin recipe on the hippocampus in a rat model of diabetes-associated cognitive decline: a proteomic analysis

“…For successful intervention, it has been suggested that the sooner treatment is established, the better the treatment outcome. We therefore performed ZBPYR intervention after a relative short period of 2 months after initiation of cognitive impairment in the diabetic animals [26][27][28][29].…”

Neonatal Handling Impairs Spatial Memory and Leads to Altered Nitric Oxide Production and DNA Breaks in A Sex Specific Manner

“…In the hippocampus, NADPHd-positive cells were counted in the pyramidal layer of Ammon's horn and the dentate gyrus totally. The staining pattern of NADPH-d positive cells was consistent with previous reports from the literature [33,34]. Results were expressed as mean number of cells/mm 2 and are shown in Table 1.…”

Comparison on hypoglycemic and antioxidant activities of the fresh and dried Portulaca oleracea L. in insulin-resistant HepG2 cells and streptozotocin-induced C57BL/6J diabetic mice

“…The mice in all groups were fed with standard rat chow and tap water ad libitum. Before the experiment, the mice were fasted overnight, and then injected with a single intraperitoneal dose of STZ (35 mg/kg) (Comin et al, 2010) which was freshly dissolved in sodium citrate buffer (pH ¼ 4.5). The same dose of sodium citrate buffer was injected for normal control.…”