Volkswirtschaftliche Bedeutung der postoperativen Harninkontinenz

Lent, V.; Schultheis, Molly

doi:10.1007/s00120-015-3856-6

Cited by 6 publications

(6 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…25 Lent et al 26 showed that the costs of the direct and indirect consequences of the PPI in Germany in 2013 were estimated at 71.8 million €, which was more than the costs of the RP itself, which amounted to 69.8 million €. 26 Therefore, it is important to reduce the possibility of PPI to a minimum. It has already been shown that preoperative profilometric data can be a significant indicator of continence recovery after RP.…”

Section: Resultsmentioning

confidence: 99%

Urethral pressure profile before radical prostatectomy as a predictor of early postoperative continence

Bakula

Hudolin

Mitrović

et al. 2022

Neurourology and Urodynamics

View full text Add to dashboard Cite

Objective: Urinary incontinence (UI) is one of the most common complications of radical prostatectomy (RP). Impaired urethral sphincter function is generally considered to be the most important contributing factor for UI; however, the mechanism of onset and recovery of urinary continence has not been fully elucidated. The objective of this research was to evaluate preoperative functional urethral length (FUL) and maximum urethral closure pressure (MUCP) as early continence recovery predictors after open retropubic RP (ORRP).Methods: The research was conducted on a group of 43 patients with localized prostate cancer (PCa) in the period from July 2019 to May 2021. The urodynamic method of urethral pressure profile (UPP) was used to assess FUL and MUCP, and correlate with the postprostatectomy continence recovery. The severity of UI and bothersome were assessed using fully validated International Consultation on Incontinence Questionnaire – Urinary Incontinence Short Form (ICIQ‐UI SF) and number of pads used in 24 h. Patients were interviewed about the use of urinary pads and asked to fill out the ICIQ‐UI SF before and 2, 8, 16 and 24 weeks after ORRP.Results: The median value of FUL (mm) and MUCP (cmH2O) was 69 (28–94) and 76 (16–223), respectively. Correlation and linear regression showed a statistically significant negative correlation between preoperative values of FUL and MUCP with ICIQ symptom score and the number of pads used per day at the four observed time intervals (p < 0.05). Such a result showed that patients with higher preoperative FUL and MUCP values were more likely to recover urinary continence earlier. A value of 65 mm for FUL and 80 cmH2O for MUCP proved to be the cut‐off values for continence recovery in 24 weeks after ORRP.Conclusion: Preoperatively evaluated FUL and MUCP seem to be valuable prognostic factors for early continence recovery after ORRP. Further investigation on a larger patient cohort is needed to evaluate the role of UPP in the preoperative management of patients with PCa.

show abstract

Section: Resultsmentioning

confidence: 99%

Urethral pressure profile before radical prostatectomy as a predictor of early postoperative continence

Bakula

Hudolin

Mitrović

et al. 2022

Neurourology and Urodynamics

View full text Add to dashboard Cite

show abstract

“…However, other studies, not included in the review have examined costs in patients with these conditions. For example, one publication (excluded from the current review as is was not published in English) estimated that in Germany the direct and indirect costs associated with urinary incontinence following prostatectomy are approximately EUR 71.8 million [73]. Similarly, figures from the UK estimate that on a per patient level, the annual cost of erectile dysfunction is GBP 335 [74].…”

Section: Discussionmentioning

confidence: 99%

Literature review of the burden of prostate cancer in Germany, France, the United Kingdom and Canada

Smith-Palmer¹,

Takizawa²,

Valentine³

2019

BMC Urol

View full text Add to dashboard Cite

BackgroundProstate cancer is the most frequently reported cancer in males in Europe, and is associated with substantial morbidity and mortality. The aim of the current review was to characterize the clinical, economic and humanistic burden of disease associated with prostate cancer in France, Germany, the UK and Canada.MethodsLiterature searches were conducted using the PubMed, EMBASE and Cochrane Library databases to identify studies reporting incidence and/or mortality rates, costs and health state utilities associated with prostate cancer in the settings of interest. For inclusion, studies were required to be published in English in full-text form from 2006 onwards.ResultsIncidence studies showed that in all settings the incidence of prostate cancer has increased substantially over the past two decades, driven in part by increased uptake of prostate specific antigen (PSA) screening leading to earlier identification of tumors, but which has also led to over-treatment, compounding the economic burden of disease. Mortality rates have declined over the same time frame, driven by earlier detection and improvements in treatment. Both prostate cancer itself, as well as treatment and treatment-related complications, are associated with reduced quality of life.ConclusionsProstate cancer is associated with a significant clinical and economic burden, whilst earlier detection and aggressive treatment is associated with improved survival, over-treatment of men with indolent tumors compounds the already significant burden of disease and treatment can lead to long-term side effects including impotence and impaired urinary and/or bowel function. There is currently an unmet clinical need for diagnostic and/or prognostic tools that facilitate personalized prostate cancer treatment, and potentially reduce the clinical, economic and humanistic burden of invasive cancer treatment.Electronic supplementary materialThe online version of this article (10.1186/s12894-019-0448-6) contains supplementary material, which is available to authorized users.

show abstract

“…Urinary incontinence has a significant economic cost. The economic burden of urinary incontinence following radical prostatectomy is comparable to that of the instigating surgery (Lent 2015). The estimated economic burden of managing urinary incontinence in men in the USA was USD 18.8 billion (USD 18,800 million, USD 1998/1999), with a trend showing a rapid increase for men above the age of 65 years (Stothers 2005).…”

Section: Description Of the Conditionmentioning

confidence: 99%

Conservative interventions for managing urinary incontinence after prostate surgery

Johnson

Mamoulakis

Stoniute

et al. 2023

Cochrane Database of Systematic Reviews

View full text Add to dashboard Cite

show abstract

Volkswirtschaftliche Bedeutung der postoperativen Harninkontinenz

Cited by 6 publications

References 19 publications

Urethral pressure profile before radical prostatectomy as a predictor of early postoperative continence

Urethral pressure profile before radical prostatectomy as a predictor of early postoperative continence

Literature review of the burden of prostate cancer in Germany, France, the United Kingdom and Canada

Conservative interventions for managing urinary incontinence after prostate surgery

Contact Info

Product

Resources

About