Voltammetric immunoassay of human IgG based on the release of cadmium(II) from CdS nanocrystals deposited on mesoporous silica nanospheres

Guo, Peng; Wang, Yun; Chen, Zhichao; Jin, Tianqi; Fu, Li; Lin, Cheng‐Te; Lai, Guosong

doi:10.1007/s00604-018-3142-6

Cited by 5 publications

(2 citation statements)

References 35 publications

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“…131 In addition, a nanocomposite was described that was inexpensively prepared by in situ deposition of CdS nanocrystals on mesoporous silica nanospheres (MSNs), and its use in an electrochemical immunoassay of human immunoglobulin G based on the release of cadmium(II) from CdS nanocrystals deposited on mesoporous silica nanospheres. 132 As an efficient photocatalyst and effective antibacterial agent, Novel nanocomposite derived from ZnO-CdS QDs embedded crosslinked chitosan was prepared. The nanocomposite demonstrates outstanding efficacy towards the photocatalytic degradation of cationic dyes [malachite green (MG), and safranin (SF)] and toxic organic molecule 2,4-dichloro phenol (2,4-DCP) under the exposure of sunlight.…”

Section: Advanced Sensing Materials Used In Direct Sensors and Comple...mentioning

confidence: 99%

Review—Insights into the Developments of Nanocomposites for Its Processing and Application as Sensing Materials

Said

Hasan

Abdelzaher

et al. 2020

J. Electrochem. Soc.

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The scope of this review is limited for advanced sensing materials and their applications. New materials, such as, engineered polymers, metals oxides, alloys, chalcogenides, nanostructured and hierarchical carbons regularly propel researchers and engineers to naturally test and compare them to existing sensors of diverse sorts. Nowadays, nanocomposite has ended up one of the foremost prevalent materials with potential applications in various ranges, including batteries with greater power output, flexible batteries, making lightweight sensors, photocatalysis and making tumors easier to see and remove. Furthermore, nanocomposites offer new technology and business opportunities for all sectors of industry. On the other hand, nanocomposites offer new innovation and commerce openings for all divisions of industry, a look through the pages of science and designing writing appears that using of nanocomposites for rising innovations speaks to one of the foremost dynamic regions of advancement all through the areas of life sciences, material science, chemistry, physics and related advances.

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Section: Advanced Sensing Materials Used In Direct Sensors and Comple...mentioning

confidence: 99%

Review—Insights into the Developments of Nanocomposites for Its Processing and Application as Sensing Materials

Said

Hasan

Abdelzaher

et al. 2020

J. Electrochem. Soc.

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“…Utilizing the semiconductor nanomaterials as signal carriers of PL and MRRS to design the dual-mode detection strategy may be a solution to simplify the preparation procedures and perform the dual-mode detection with good reproducibility. As a typical II–VI semiconductor material, CdS shows prominent performance in the field of biolabeling and biodetection [ 25 , 26 ]. More importantly, the bandgap of CdS is 2.42 eV which is in accordance with the energy of 488 nm (2.54 eV) laser.…”

Section: Introductionmentioning

confidence: 99%

Photoluminescent and multi-phonon resonance Raman scattering dual-mode immunoassays based on CdS nanoparticles for HIgG detection

Wen

Ding

et al. 2022

Microchim Acta

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A dual-mode immunoassay strategy based on CdS nanoparticles as signal probes with both of photoluminescent (PL) and multi-phonon resonance Raman scattering (MRRS) properties was developed. Simplified structural design and preparation were achieved due to the intrinsic integration of PL and MRRS dual signals in the single-unit CdS nanoprobes. Human immunoglobulin G (HIgG) was sensitively and specifically detected using the proposed PL-MRRS dual-mode strategy. The linear relationship between the HIgG concentration and the intensity of 707 nm PL peaks/300 cm −1 MRRS peaks under the excitation of 488 nm laser was established. The limit of detection was 0.93 fg mL −1 for PL and 1.10 fg mL −1 for MRRS. In comparison with previous IgG detection methods, the proposed method exhibited prominent advantages in detection sensitivity and working range with good stability and repeatability. An internal self-calibration was realized which ensured the accuracy and reliability of detection results. Both results of specificity experiments and serum sample analysis further confirmed the feasibility of the designed immunoassay strategy in practical serological detection. Graphical abstract Supplementary Information The online version contains supplementary material available at 10.1007/s00604-022-05530-z.

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Simple “Signal‐Off” Electrochemical Aptasensor Based on Aptamer‐Cu₃(PO₄)₂ Hybrid Nanoflowers/Graphene Oxide for Carcinoembryonic Antigen Detection

Zou

Guo

et al. 2020

ChemElectroChem

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A signal-off aptasensor was described based on well-designed aptamer-Cu 3 (PO 4 ) 2 hybrid nanoflowers&graphene oxide composites (aptamer-Cu 3 (PO 4 ) 2 HNF&GO) as an effective sensing platform and molybdophosphate precipitation as the signaling element. The aptamer, as the biorecognition unit grafted on aptamer-Cu 3 (PO 4 ) 2 HNF&GO by the specificity of streptavidin and biotin, captured the carcinoembryonic antigen (CEA) through specific interaction. The molybdophosphate precipitation were formed by the reaction of the aptamer-Cu 3 (PO 4 ) 2 HNF&GO with molybdate (MoO 4 2 À ). However, the CEAaptamer bioconjugate layer films not only hinder electron transfer on the sensing interface, but also impede the formation of molybdophosphate precipitation, resulting that the current signal significantly decreased. So, a simple aptasensor for CEA was constructed with high sensitivity and signal-off model. Under optimal experimental conditions using square wave voltammetry (SWV), the response peak currents decreases linearly with the logarithm of CEA concentrations in the range from 10 fg mL À 1 to 500 ng mL À 1 . Also, the feasibility of its applications has also been demonstrated in the analysis of clinical serum samples.

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Voltammetric immunoassay of human IgG based on the release of cadmium(II) from CdS nanocrystals deposited on mesoporous silica nanospheres

Cited by 5 publications

References 35 publications

Review—Insights into the Developments of Nanocomposites for Its Processing and Application as Sensing Materials

Review—Insights into the Developments of Nanocomposites for Its Processing and Application as Sensing Materials

Photoluminescent and multi-phonon resonance Raman scattering dual-mode immunoassays based on CdS nanoparticles for HIgG detection

Simple “Signal‐Off” Electrochemical Aptasensor Based on Aptamer‐Cu₃(PO₄)₂ Hybrid Nanoflowers/Graphene Oxide for Carcinoembryonic Antigen Detection

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Voltammetric immunoassay of human IgG based on the release of cadmium(II) from CdS nanocrystals deposited on mesoporous silica nanospheres

Cited by 5 publications

References 35 publications

Review—Insights into the Developments of Nanocomposites for Its Processing and Application as Sensing Materials

Review—Insights into the Developments of Nanocomposites for Its Processing and Application as Sensing Materials

Photoluminescent and multi-phonon resonance Raman scattering dual-mode immunoassays based on CdS nanoparticles for HIgG detection

Simple “Signal‐Off” Electrochemical Aptasensor Based on Aptamer‐Cu3(PO4)2 Hybrid Nanoflowers/Graphene Oxide for Carcinoembryonic Antigen Detection

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Simple “Signal‐Off” Electrochemical Aptasensor Based on Aptamer‐Cu₃(PO₄)₂ Hybrid Nanoflowers/Graphene Oxide for Carcinoembryonic Antigen Detection