What is the mechanism for melasma that so commonly accompanies human pregnancy?

Costin, Gertrude‐Emilia; Birlea, Stanca-Ariana

doi:10.1080/15216540500417020

Cited by 10 publications

(5 citation statements)

References 25 publications

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“…7,8,11 Epidermal melasma was the commonest variety seen which is also in accordance with other studies, while dermal type was the least common i.e. only one case which is nearly similar to the findings by perez et al…”

Section: Discussionsupporting

confidence: 82%

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Hormonal Evaluation in Females Having Melasma

Ali¹,

Bali²,

Sharma³

2015

jemds

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BACKGROUND:Melasma is a commonly acquired hyperpigmentation which present as irregular, light to dark brown macules on sun exposed skin due to various etiological factors including hormonal imbalance. AIM: To assist the level of various hormones and study the clinical and hormonal correlation in patients of melasma. METHODS: 50 female patients of melasma between age group 18-50 with equal number of age matched females with no signs of melasma, hirsutism and any other endocrinal abnormality, were enrolled. They were examined by woods' lamp to see the type of melasma whether epidermal, dermal or mixed. 10 ml of venous blood sample was drawn after overnight fasting on 3 rd -5 th day of the menstrual cycle in mid follicular phase for the assessment of LH, FSH, Prolactin, Estradiol and Progesterone by chemiluminescence method. RESULT: Out of 50 patients, 8 patients had deranged level of LH, 7 patients had deranged level of FSH, 14 patients had deranged prolactein, 18 patients had deranged estradiol and 6 patients had deranged level of progesterone. 70% patients were married and belong to age group of 31-40 years. 18 % patients has onset of melasma during pregnancy while 52% patients after the delivery. CONCLUSIONS: LH, estradiol and progesterone are found to be contributory factors in development of melasma.

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Section: Discussionsupporting

confidence: 82%

“…The duration of sun exposure was 1-3 hours in 60% of patients which is clearly seen as an important triggering factor in other studies also. 11 The UV exposure during summer months has been reported to produce induction or exacerbation of Melasma.…”

Section: Discussionmentioning

confidence: 99%

Hormonal Evaluation in Females Having Melasma

Ali¹,

Bali²,

Sharma³

2015

jemds

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“…Melasma is linked to other conditions and situations. It frequently arises during pregnancy, in which case it is referred to as chloasma, or the mask of pregnancy 3 . Chloasma usually fades a few months after delivery.…”

Section: Discussionmentioning

confidence: 99%

Melasma

Scheinfeld

2007

Skinmed

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“…Population‐based studies in pregnant women have revealed a varying melasma prevalence of 10–70%, suggesting that other factors, such as ethnicity and sun exposure, are involved in its development 17–20 …”

Section: Introductionmentioning

confidence: 99%