When Computers Can Kill—Two Unusual Cases of “E-Thrombosis”

Doctor, Nausheen Edwin; Seth, Puneet

doi:10.4236/ijcm.2018.94029

Cited by 4 publications

(4 citation statements)

References 17 publications

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“…Thirteen articles were included in the current review (Table 2 and Supplementary table 2), including four prospective studies [36][37][38][39] with large study size (up to 389,530 participants) and about 20 years of follow-up, four case-control studies, two conducted in the same initial population 40 41 including respectively 97 and 192 cases, one among insured bank staff 42 , and one from clinic services 43 and five case-reports [44][45][46][47][48] . All the studies adjusted their analyses on gender and age while other confounders, known as causal risk factors of VTE, were heterogeneously considered.…”

Section: Venous Thromboembolism (Deep Vein Thrombosis and Pulmonary Ementioning

confidence: 99%

Lower limb venous and arterial peripheral diseases and work conditions: systematic review

et al. 2020

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ObjectivesThe individual peripheral vascular disease risk factors are well documented, but the role of work conditions remains equivocal. This systematic review aims to assess relationships between lower limb peripheral venous diseases (lower limb varicose veins (LLVV), venous thromboembolism (VTE) comprising deep vein thrombosis and pulmonary embolism), peripheral arterial disease (intermittent claudication, aortic dissection, aortic aneurysm) and occupational constraints among working adults.MethodsSeveral databases were systematically searched until February 2019 for observational studies and clinical trials. Preferred Reporting Items for Systematic Reviews and Meta-Analyses method was used for article selection. Quality assessment and risk of bias were evaluated using Strengthening the Reporting of Observational Studies in Epidemiology and Newcastle-Ottawa scales.ResultsAmong the 720 screened articles, 37 remained after full-text evaluation. Among the 21 studies on LLVV, prolonged standing was significantly associated to a higher risk of varicose veins with a threshold probably around >3 to 4 hours/day but exposure duration in years was not sufficiently considered. Seated immobility was often observed in workers, with no sufficient evidence to prove that prolonged sitting at work is related to VTE. Carrying heavy loads, stress at work and exposure to high temperatures have emerged more recently notably in relation to varicose veins but need to be better explored. Only three studies discussed the potential role of work on peripheral arterial disease development.ConclusionsAlthough some observational studies showed that prolonged standing can be related to varicose veins and that seated immobility at work could be linked to VTE, very little is known about peripheral arterial disease and occupational constraints. Clinical trials to determine preventive strategies at work are needed.PROSPERO registration numberCRD42019127652.

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Section: Venous Thromboembolism (Deep Vein Thrombosis and Pulmonary Ementioning

confidence: 99%

Lower limb venous and arterial peripheral diseases and work conditions: systematic review

et al. 2020

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“…Braithwaite et al described the case of a 42-year-old man who developed bilateral pulmonary emboli accompanied with right heart strain, after having spent 48 consecutive hours playing on-line computer games, leaving his chair just for toilet breaks (12). More recently, Doctor and Seth described two other cases of venous thrombosis developing after prolonged computer use (13). The former case was a 50-year-old male, software professional, who developed a DVT in the iliac, femoral and popliteal veins of the left leg after having worked on his computer for 12 consecutive hours, with less than 4 breaks.…”

Section: Case Reportsmentioning

confidence: 99%

e-thrombosis: epidemiology, physiopathology and rationale for preventing computer-related thrombosis

Lippi¹,

Mattiuzzi²,

Favaloro³

2018

Ann. Transl. Med.

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The large availability of computers (personal, laptop and tablet) has revolutionized human life more than any other discovery or invention over the past century. Nevertheless, prolonged use of computers may both directly and indirectly promote the onset of some serious human pathologies, thus including venous thromboembolism (VTE). Convincing epidemiological and biological evidence has been published that computer-related thrombosis (also known as "e-thrombosis") should now be regarded as an independent clinical entity, deserving enhanced healthcare focus and interventions, due to the growing worldwide diffusion of computer devices, which may ultimately contribute to enhance the risk of computerrelated thrombosis, and turn it from a relatively rare disease to a noticeably frequent pathology. A set of preventive measures can thus be suggested, such as designing and setting up ergonomically suitable computer workstations, using comfortable sitting positions, avoiding long and uninterrupted computer-seated immobility, and avoiding the wearing of restrictive clothing on the legs. Reinforced measures should then be advised in patients with acquired, or inherited prothrombotic conditions, in whom the risk of computerrelated thrombosis may be substantially magnified.

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“…(10) Deep vein thrombosis occurs when a person sits for at least 8 hours and at least 3 hours without interruption. (10,13,20) After 3 hours of sitting without interruption, blood flow disturbance will occur. (20) Decreased blood flow will cause hypoxia, activate blood clotting factors, and cause a hypercoagulable state that triggers thrombus *Chi-Square test the coagulation pathway, thereby increasing the risk of DVT.…”

Section: Discussionmentioning

confidence: 99%

“…(12) Nausheen et al reported a case of DVT in Singapore in men aged 50 years due to prolonged sitting in front of a computer while working for an average of 12 hours per day. (13) However, Johannesen et al's study in Denmark on a population aged 20-65 years stated that there was no relationship between sitting duration and risk of DVT. (14) Body mass index is also closely related to the risk of DVT.…”

Section: Introductionmentioning

confidence: 98%

Hubungan Durasi Duduk Dan Indeks Massa Tubuh Terhadap Risiko Deep-Vein Thrombosis Karyawan

Shafia

Wartono

2022

J Biomedika Kesehat

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LATAR BELAKANG Deep vein thrombosis (DVT) adalah keadaan terbentuknya bekuan darah dalam sistem sirkulasi vena dalam terutama pada vena femoralis dan vena poplitea. Penyakit tersebut dipengaruhi berbagai macam faktor di antaranya yaitu obesitas dan gaya hidup sedenter seperti duduk dalam durasi yang lama. Karyawan yang menghabiskan sebagian besar waktunya untuk duduk bekerja di kantor memiliki risiko mengalami keluhan ini. Berbagai penelitian sebelumnya menunjukkan hasil yang berbeda, dengan demikian diperlukan penelitian lebih lanjut. METODE Penelitian ini menggunakan studi observasional analitik dengan metode cross-sectional. Dilakukan pada 90 karyawan di Kantor Pusat Bank BTN Jakarta pada bulan Oktober hingga November 2021. Data dikumpulkan dengan wawancara menggunakan kuesioner OSPAQ untuk menilai durasi duduk, Kriteria Wells untuk menilai risiko DVT, dan perhitungan indeks massa tubuh (IMT). Pemilihan sampel dilakukan dengan teknik simple random sampling, dan analisis menggunakan chi-square. HASIL Responden laki-laki (60%) lebih banyak dari responden perempuan (36%). Didapatkan 4,4 % karyawan memiliki IMT kurus, 52,2% karyawan memiliki IMT normal, dan 43,3% karyawan memiliki IMT gemuk. Rerata durasi duduk responden yaitu 2,6 jam/hari tanpa interupsi .Tidak terdapat hubungan antara durasi duduk (p = 0,903) dengan risiko deep vein thrombosis. Terdapat hubungan antara indeks massa tubuh (p = 0,008) dengan risiko deep vein thrombosis. KESIMPULAN Indeks massa tubuh di atas normal merupakan risiko terjadinya deep vein thrombosis, namun penyakit tersebut tidak dipengaruhi oleh durasi duduk yang lama. Kata Kunci: Durasi duduk, Indeks massa tubuh, Deep vein thrombosis, Karyawan.

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When Computers Can Kill—Two Unusual Cases of “E-Thrombosis”

Cited by 4 publications

References 17 publications

Lower limb venous and arterial peripheral diseases and work conditions: systematic review

Lower limb venous and arterial peripheral diseases and work conditions: systematic review

e-thrombosis: epidemiology, physiopathology and rationale for preventing computer-related thrombosis

Hubungan Durasi Duduk Dan Indeks Massa Tubuh Terhadap Risiko Deep-Vein Thrombosis Karyawan

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