Paper presents an overview of recent results on novel CdSe quantum dot (QD) fabrication techniques with the main impact on a stressor-controlled self-organization process resulting in nucleation of real CdSe QDs optically active up to room temperature, with a narrower size distribution, a higher density and a high Cd content. The main idea of the stressor-controlled epitaxy is an intentional introduction of a superstrained fractional monolayer of the much higher lattice-mismatch compound -stressor -to create strong local stress fields on the growth surface which govern self-assembling of the main QD material. The studies are performed on a type-II non-common atom CdSe/BeTe system, where CdTe (∆a/a ~ +14%) and BeSe (∆a/a ~ -10%) interface bonds play a role of intrinsic stressors. Both experimental data (growth, structural and optical characterization) and Monte Carlo simulation of the growth process are presented.