Y-chromosomal STR haplotype diversity in a sample from the Metropolitan Area of Buenos Aires (Argentina)

Parolín, María Laura; Avena, Sergio Alejandro; Dejean, Cristina Beatriz; Jaureguiberry, Stella Maris; Sambuco, Lorena Andrea; Carnese, Francisco R.

doi:10.31048/1852.4826.v5.n1.9125

Cited by 7 publications

(6 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…On the other hand, haplogroup R1a would represent a migratory pulse of Slavic origin that would have occurred more narrowly during the first decades of the 20th century (Vidart & Pi Hugarte, 1969). In practically all South American cosmopolitan populations, R1b is the most frequent haplogroup (Cárdenas et al, 2015; Parolin et al, 2012; Resque et al, 2016). This represents a common Western European and fundamentally Iberian genetic background for the Latin American continent.…”

Section: Discussionmentioning

confidence: 99%

“…The highest frequencies of Native lineages were found in Northwestern populations (32%) (Dipierri et al, 1998; Ramallo et al, 2009). In a sample from Buenos Aires, 6% of paternal lineages were found to be of Native American origin (Parolin et al, 2012) and in Brazil, these lineages account for 3%, with the highest frequencies found in the Amazonian region (8%), where most of the Native population is currently located (Resque et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Insights into the Y chromosome human diversity in Uruguay

Mut¹,

Bertoni

Sapiro³

et al. 2023

American J Hum Biol

View full text Add to dashboard Cite

BackgroundWith regard to the origin of its population and microevolutionary processes, Uruguay exhibits distinctive features that distinguish it from other countries in Latin America, while at the same time sharing several similarities. In this article, we will focus on the variability of paternal genetic lineages in two geographical regions with different histories that can be considered as examples of distinct populations for the continent. In general terms, the genetic diversity is a result of different demographic processes related to the American conquest and colonisation. These resulted in distinct ancestral components which vary geographical and depend on the distribution by sex within these components. In Uruguay, native maternal haplogroups are significantly more frequent in the North. Although there are several studies about the geneticvariability of Uruguay, little is known about male genetic lineages.AimsThe aim of this work is to present an updated study of the male genetic variability of the Uruguayan population.MethodsWe analyzed 13 biallelic markers and 27 STRs located in the male‐specific region of the Y chromosome for 157 males: 98 from the capital, Montevideo, and 59 from Tacuarembó.ResultsAlmost all haplogroups found in both locations are European (99% and 93.2% respectively). One Sub‐Saharan African haplogroup was found in Montevideo (1%) and 2 in Tacuarembó (3%), while Native haplogroups were found only in Tacuarembó, evidencing a strong sex‐biased admixture. By crossing genetic and genealogical information we could relate European haplogroups with different waves and times of migrations.DiscussionNetwork analysis indicated a very diverse male population, suggesting that European migrants came from heterogeneous geographic locations and in different waves. Tacuarembó has closer population affinities with Iberian populations while Montevideo is more diverse. Male population expansion expansion, can be explained by the large number of migrants that arrived during the XIX century and the first half of the XX century.ConclusionsThe Uruguayan male gene pool is the result of several migration waves with diverse origins, with strong sex‐biased admixture that can be explained by the European migration, the violence against the indigenous males, and the segregation of the Africansadmixture that can be explained due to European migration, violence against Natives, and segregation against African males.admixture that can be explained due to European migration, violence against Natives, and segregation against African males.admixture that can be explained due to European migration, violence against Natives, and segregation against African males.admixture that can be explained due to European migration, violence against Natives, and segregation of hte Africans.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Insights into the Y chromosome human diversity in Uruguay

Mut¹,

Bertoni

Sapiro³

et al. 2023

American J Hum Biol

View full text Add to dashboard Cite

show abstract

“…L opez Camelo et al (1996) were the first to include the African genetic component in their analyses, thus increasing the complexity of the approaches under a three-hybrid model. Since then, a scheme of three-way admixture (i.e., with European, Native American, and African parental populations) was settled and remained identical in practically all miscegenation studies in Argentina (Carnese et al, 2011;García et al, 2015;Luisi et al, 2020;Parolin et al, 2012;Pauro et al, 2010;Salas et al, 2008, among others), not because all these works ignored the historical and current migratory processes from other origins, but because the limitations of the employed methods and/or availability of fine-scale data leveraged as reference made it difficult to prove.…”

Section: Introductonmentioning

confidence: 99%

Genetic and self‐perceived ancestries in Argentina: Beyond the three‐hybrid model

Ruderman

Luisi

Paschetta

et al. 2023

American Journal of Biological Anthropology

View full text Add to dashboard Cite

Objectives The increased availability of genome‐wide data allows capturing the fine genetic structure of present days populations. Here we analyze the genetic ancestry at a fine scale of an Argentinean Patagonia population to understand the origins beyond the three‐hybrid model, and to compare these results with volunteers' self‐perceived ancestry in a broad context encompassed by historical and familiar information. Materials and Methods We compare high‐throughput genotyping data for 92 individuals that we generated to data sets from the literature by applying fully haplotype‐based methods to examine patterns of human population substructure. The volunteers filled out a semi‐structured questionnaire, including questions about their history, ancestors, and self‐perceived ancestry. Finally, we used non‐parametric tests in order to compare genomic ancestry against self‐perception. Results Genetic ancestry from Iberian populations accounted for 0.176 (Spain and Basque origins), while the component associated with Italian populations accounted for 0.140. We observed a 0.169 Native American genetic ancestry. Participants significantly over‐ and under‐ self‐perceived Native American and European origins, respectively. Components of origins from North Africa to Central South Asia accounted for 0.225 of the genetic ancestry in the sample, with significantly higher proportions for people that mentioned such origins in their genealogical history. Discussion We captured the fine‐genetic architecture of a Puerto Madryn population sample in Chubut province, showing that self‐perceived ancestry remains a poor proxy for genetic ancestry. The presence of North Africa to Central South Asia components and its correlate with self‐perception of these origins justifies its inclusion in future miscegenation studies in Argentina.

show abstract

“…Para el país en general, el aporte genético europeo es dominante (65%-79%), siendo la contribución amerindia la segunda en porcentaje (17%-31%) y el aporte africano el mínimo (2%-4%) (Seldin et al, 2007;Corach et al, 2010;Avena et al, 2012, entre otros). A grandes rasgos, la región central de Argentina presenta una mayor contribución europea, y las del Norte y el Sur poseen un mayor aporte nativo americano (Martínez-Marignac et al, 1999;Avena et al, 2001;Dipierri et al, 1997;Alfaro et al, 2004;Gonzales e Ianiro, 2012;Parolin et al, 2013;García et al 2015, entre otros). Por su parte, el aporte africano alcanza su máximo en las provincias de La Rioja y Santiago del Estero, de acuerdo con las rutas de traslado de esclavos en tiempos coloniales (Alfaro et al, 2005).…”

Section: Población Argentinaunclassified

“…Dentro de la provincia de Buenos Aires (incluyendo a la ciudad de Buenos Aires), se han reportado porcentajes de ancestría europea entre 68 y 81%, nativa entre 15 y 29% y africana entre 0 y 4% (Fejerman et al, 2005;Resano et al, 2007;Corach et al, 2010;Avena et al, 2012;Parolin et al, 2013). La provincia muestra en promedio un 76% de contribución europea, y contribuciones nativas y africanas que no se diferencian significativamente del promedio ya reportado para el país (Avena et al, 2012).…”

Section: Población Bonaerenseunclassified

Variación genética del color del iris en la población bonaerense

Hohl

View full text Add to dashboard Cite

El color de los ojos es un carácter fenotípico conspicuo de los seres humanos, siendo sus distintas variantes útiles en la descripción de los individuos. Es un carácter cuantitativo complejo, de herencia poligénica. Como todo rasgo genético cuantitativo, puede sufrir variaciones en las poblaciones donde ocurre mezcla de diferente ancestría, dado que las poblaciones de distintas procedencias pueden portar diferentes variantes o frecuencias alélicas en genes que influyen en la determinación del color del iris. Actualmente, la información sobre estos genes en poblaciones con ancestría mixta y, particularmente en la población de nuestro país, es escasa. Debido a que este carácter es determinado genéticamente, su análisis contribuye a la identificación de individuos en el ámbito de la Genética Forense. Existen sistemas de predicción desarrollados y estandarizados a partir de información genética de poblaciones europeas; sin embargo, para usar un sistema de predicción, éste debe estar validado en la población a analizar. Este trabajo trata el análisis de la determinación genética del color de los ojos en la población argentina, teniendo en cuenta su historia migratoria, para una futura aplicación en pruebas de identificación de personas. Se analizaron fotografías digitales y muestras de ADN de individuos donantes voluntarios de la población bonaerense. La información genética estudiada comprendió marcadores determinantes del color del iris, como también marcadores de ancestría. En la población estudiada los sistemas de predicción actualmente disponibles no resultaron totalmente satisfactorios dado que, en particular, los colores intermedios (verdes) fueron los más difíciles de predecir, y a su vez los más frecuentes en nuestra población. Esto en parte podría explicarse por la ancestría mixta, ya que se determinó una relación entre la ancestría y el color, y entre la ancestría y las predicciones erróneas de uno de los sistemas. Posiblemente, el aporte nativo, poco estudiado actualmente respecto al color del iris, estaría influenciando estos resultados.

show abstract

Y-chromosomal STR haplotype diversity in a sample from the Metropolitan Area of Buenos Aires (Argentina)

Cited by 7 publications

References 33 publications

Insights into the Y chromosome human diversity in Uruguay

Insights into the Y chromosome human diversity in Uruguay

Genetic and self‐perceived ancestries in Argentina: Beyond the three‐hybrid model

Variación genética del color del iris en la población bonaerense

Contact Info

Product

Resources

About