Yerba Mate (Ilex paraguariensis) a potential food antibacterial agent and combination assays with different classes of antibiotics

Fayad, Elie; El-Sawalhi, Sabah; Azizi, Lamia; Beyrouthy, Marc El; Abdel-Massih, Roula M.

doi:10.1016/j.lwt.2020.109267

Cited by 22 publications

(9 citation statements)

References 20 publications

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“…Nesse sentido, o uso concomitante da planta pode estar interferindo no funcionamento da medicação de dois pacientes, os quais utilizam propranolol e losartana para tratamento da hipertensão (EKPENYONG et al, 2015;AVOSEH et al, 2015). Ademais, um desses pacientes relatou que também sofre arritmias cárdicas frequentes, entretanto, faz uso de Ilex paraguariensis que deve ser evitada por pessoas com ansiedade, pressão alta e problemas cardíacos (FAYAD et al, 2020).…”

Section: Resultsunclassified

Estudo Da Atividade Hipoglicemiante Com Base No Fitoextrato Produzido a Partir De Bauhinia Forficata Link, 1821 E Cecropia Pachystachya Trécul, 1847

Barreto¹,

Barreto²,

Cruz³

2020

Farmácia Na Atenção E Assistência À Saúde 2

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Direitos para esta edição cedidos à Atena Editora pelos autores.Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons.Atribuição-Não-Comercial-NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0). O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores, inclusive não representam necessariamente a posição oficial da Atena Editora. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais.Todos os manuscritos foram previamente submetidos à avaliação cega pelos pares, membros do Conselho Editorial desta Editora, tendo sido aprovados para a publicação.A Atena Editora é comprometida em garantir a integridade editorial em todas as etapas do processo de publicação. Situações suspeitas de má conduta científica serão investigadas sob o mais alto padrão de rigor acadêmico e ético.

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Section: Resultsunclassified

Estudo Da Atividade Hipoglicemiante Com Base No Fitoextrato Produzido a Partir De Bauhinia Forficata Link, 1821 E Cecropia Pachystachya Trécul, 1847

Barreto¹,

Barreto²,

Cruz³

2020

Farmácia Na Atenção E Assistência À Saúde 2

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“…The higher inhibition observed in the present study may be attributed to the use of high-intensity ultrasound during the extraction procedure, which may have induced the additional release of other chemicals, thus contributing in a synergistic way to the antimicrobial activity. Similarly, Fayad et al (2020) evaluated the MIC values of an aqueous extract of yerba mate, obtained by hot water immersion (70°C, 2 hr, 1 g leaves, 3.6 ml water) against different bacteria. They reported MIC values 1.88-3.75 mg/ml extract and 2.5-10 mg/ml extract against different strains of Staphylococcus aureus and Acinetobacter baumannii, respectively.…”

Section: Mic and Mbc Testing Of The Ymesmentioning

confidence: 99%

“…In particular, the maté tea, a hot infusion elaborated with industrially processed yerba mate (Ilex paraguariensis, St Hill) leaves, is widely consumed as a social beverage in some Latin American countries. Multiple beneficial properties to the human health have been linked to maté tea consumption, including antioxidant and antimicrobial properties (Fayad et al, 2020). Moreover, there is a growing interest in manufacturing leafy green-based juices due to their health-promoting and lowcalorie attributes (Biancaniello et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

“…The plant material at this stage is frequently denominated "aged-canchada" yerba mate. Despite the fact that several studies focused their research on the antimicrobial properties of different commercial brands of yerba mate (Burris et al, 2015;Fayad et al, 2020;Prado Martin et al, 2013), no studies have been reported on the influence of different industrialization steps on the antimicrobial properties of yerba mate. Moreover, there are no studies revealing the type of structural damage on the microbial cells exposed to yerba mate extracts (YMEs).…”

Section: Introductionmentioning

confidence: 99%

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Development of extracts obtained from yerba mate leaves with different industrial processing steps: Antimicrobial capacity, antioxidant properties, and induced damage

Schenk

Ferrario

Schmalko

et al. 2021

J. Food Process. Preserv.

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This study was aimed at developing a yerba mate extract (YME) intended to be used as food additive with antioxidant and antimicrobial capacity. For the extraction, yerba mate (Ilex paraguariensis, St Hill) leaves collected from three industrial processing steps (green, unaged-canchada, and aged-canchada) were used. The aged-canchada YME exhibited higher theobromine, chlorogenic acid, caffeic acid, caffeine, and kaempferol than green YME. It was selected for further analyses as it showed the

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“…Yerba mate extracts have higher polyphenolic levels than green tea extracts and have the same level as red wine [4]. Polyphenols are correlated with antioxidant activity, anti-cancer activity [5], antibacterial activity [6], and different health benefits [7]. Case studies have shown that diets rich in fruits and vegetables are inversely correlated with cancer incidence especially gastro-intestinal tract cancers [8][9].…”

Section: Introductionmentioning

confidence: 99%

Anti-proliferative activity of yerba mate (Ilex paraguariensis) aqueous extracts on human colorectal cancer cell lines

Saleh

Othman

Elchoueiry

et al. 2021

FFHD

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Background: Yerba mate, a popular, tea-like beverage prepared from the dried leaves of Ilex paraguariensis, is widely consumed, and has several reported health benefits. Compared with other herbal teas, the effect of yerba mate on human cells in the context of cancer has not been extensively studied. The method of extraction of bioactive compounds from the yerba mate leaves plays an important role in its effect on cancer cells. Methods: In this study we assessed the viability, anti-proliferative, and apoptotic effect of the aqueous yerba mate extract, prepared using the same conditions employed for consumption, on different human colorectal cancer cell lines (Caco-2, HT-29, and HCT116) and on the non-tumorigenic human colon epithelial cell line (NCM460).Results: Cytotoxicity of aqueous yerba mate extract was studied and a dose-dependent decrease in viability was observed in all the tested cell lines. At 24 hrs., viability decreased to 19.7% with Caco-2 cells, 2.7% with HCT116, and 8.4% with HT-29 cells at a concentration of 4.8 mg/mL of yerba mate extract. The effect was less prominent on the NCM460 cell line where the viability of cells at the same concentration was 65.2%. Yerba mate extract also showed concentration-dependent anti-proliferative effects as determined by the WST-1 proliferation kit. IC50 values ranged between 0.22-0.69 mg/mL at 24 hr for cell lines tested. To study whether cell death was due to apoptosis, Caco-2 cells were stained with Annexin V-FITC assay and an increase in the percentage of late apoptotic Caco-2 cells was observed with yerba mate extract at 0.6-4.8 mg/mL. Cell cycle analysis using DNA content by flow cytometry showed an increase in the percentage of Caco-2 cells in the subG0/G1 phase and the G0/G1 phase after treatment with 2.4 mg/mL extract. Collectively, our data suggest that yerba mate aqueous extract exhibits an anti-proliferative effect on tested cell lines by inducing apoptosis. Conclusions: Yerba mate aqueous extract exhibits a strong anti-proliferative activity against adenocarcinoma cell lines studied and constitutes a promising functional food adjuvant to anti-cancer therapy. Further work is needed to identify active components and mechanisms of action. Keywords: Aqueous extract, yerba mate, anti-proliferative activity, adenocarcinoma cell lines

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Yerba Mate (Ilex paraguariensis) a potential food antibacterial agent and combination assays with different classes of antibiotics

Cited by 22 publications

References 20 publications

Estudo Da Atividade Hipoglicemiante Com Base No Fitoextrato Produzido a Partir De Bauhinia Forficata Link, 1821 E Cecropia Pachystachya Trécul, 1847

Estudo Da Atividade Hipoglicemiante Com Base No Fitoextrato Produzido a Partir De Bauhinia Forficata Link, 1821 E Cecropia Pachystachya Trécul, 1847

Development of extracts obtained from yerba mate leaves with different industrial processing steps: Antimicrobial capacity, antioxidant properties, and induced damage

Anti-proliferative activity of yerba mate (Ilex paraguariensis) aqueous extracts on human colorectal cancer cell lines

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