Yolk sac tumor in a young girl: A case report

Razzi, S.; Luisi, Stefano; Gabbanini, Massimo; Lazzeri, Lucia; Mazzini, Massimo

doi:10.1080/09513590500099065

Cited by 12 publications

(16 citation statements)

References 4 publications

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“…Of all the genital tumors, yolk sac tumors are relatively uncommon and they are mostly discovered in infants and adolescents (median age, 19 years) (3). Although they typically arise from the gonads, YSTs have already been reported in many extragonadal sites.…”

Section: Discussionmentioning

confidence: 99%

Primary Yolk Sac Tumor Arising in the Pancreas with Hepatic Metastasis: a Case Report

et al. 2010

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Extragonadal yolk sac tumor (YST) is a relatively rare entity. We describe here the case of an extragonadal YST that occurred in the pancreas with hepatic metastasis in an adult woman. The contrast enhanced CT images of the abdomen revealed a heterogeneous, solitary mass occupying the pancreatic neck and body with slightly inhomogeneous contrast enhancement. Two low-density lesions in the liver were also displayed on the CT images. The patient underwent surgery and the diagnosis of YST was pathologically verified.

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Section: Discussionmentioning

confidence: 99%

Primary Yolk Sac Tumor Arising in the Pancreas with Hepatic Metastasis: a Case Report

et al. 2010

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“…Razi et al reported a case of ovarian yolk sac tumor with a markedly elevated serum AFP level of 1156 ng/mL. 9 Case report by Eddaoulline et al also showed an increase in the patient's serum AFP level to 52,330 ng/mL.5 Serum AFP level in yolk sac tumors will increase far beyond the normal value (<10 ng/mL), which is >1000 ng/ml. Alpha-fetoprotein is normally produced by the yolk sac during embryonic development, so a severe proliferation of yolk sac tumor cells will cause an increase in serum AFP levels in almost all cases.…”

Section: Discussionmentioning

confidence: 98%

Difficulty in Diagnosing Peritoneal Fluid Cytology in Ovarian Yolk Sac Tumor Cases

Pemuda

Yenita

Mayorita

et al. 2021

AOJ

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Objective : This article objective is to describe cytology diagnosis difficulties of yolk sac tumors of the ovary.Method : Case reports and literature review.Case : The author reports the case of a 24 year old woman who complained of an enlarged stomach. Serum AFP increased to 16,519.7 U/mL. Ultrasound examination revealed solid and irregular mass of ovarian, so the conclusion was suspect ovarian carcinoma. Conclusion of CT scan examination was a solid ovarian tumor. The working diagnosis was suspect ovarian carcinoma. Optimal debulking was performed, accompanied by taking a sample from the peritoneal rinse fluid. Microscopic examination of peritoneal fluid showed the distribution and group of cells with pleomorphic nuclei, partly hyperchromatic, partly vesicular with coarse chromatin and prominent nucleoli. There were also cells with polygonal nuclei, small nuclei, basophilic and vacuole cytoplasm with a mucoid background. These cells formed a solid arrangement. Conclusion from these features was carcinoma metastases to the peritoneal fluid. Microscopic examination from tumor tissue sample showed an ovarian yolk sac tumor appearance.Conclusion : Cytologic examination of peritoneal fluid in cases of ovarian yolk sac tumor is quite difficult to determine the diagnosis. This is due to the microscopic appearance of tumor cells which often looks like a carcinoma and limited literature about this tumors in the peritoneal fluid.Keywords: Yolk sac tumor, ovary,

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“…Primary yolk sac tumor (YST) of the endometrium is very rare, and only 15 cases have been reported (1,2). This case report is the 16th case in the world.…”

Section: Introductionmentioning

confidence: 92%

Primary Yolk Sac Tumor of the Endometrium with MRI Findings: A Case Report

2020

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: Primary yolk sac tumor (YST) of the endometrium is a very rare malignant germ cell tumor, primary YST of the endometrium with detailed magnetic resonance imaging (MRI) and contrast-enhanced MRI (CE-MRI) findings have not yet been reported in the English literature. We report a 40-year-old woman presenting with irregular lower abdominal pain and dysmenorrhea for more than 5 months. MRI showed a lesion in the right side wall of the uterus. Postoperative pathology and immunohistochemistry confirmed the diagnosis of primary YST of the endometrium with the International Federation of Gynecology and Obstetrics (FIGO) system staging of IV. The signal of the tumor was complex and lacked specific characteristic. Diffusion-weighted imaging (DWI) showed that the lesion is diffuse limited, the average apparent diffusion coefficient (ADC) value of the solid component was 0.735 × 10-3 mm2/s. CE-MRI showed that the irregular lesions presented uneven and mild enhancement in the arterial stage, and continued to strengthen in the venous phase, and strengthened close to the myometrium in the delayed phase. Primary YST of the endometrium should be considered if MRI scans show an irregular lesion in the myometrium with high level of alpha-fetoprotein (AFP).

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Yolk sac tumor in a young girl: A case report

Abstract: This is an interesting case of yolk sac tumor in a young girl, at an age typical for germ cell tumor. AFP represents a valid marker resulting in a useful diagnostic tool.

Cited by 12 publications

References 4 publications

Primary Yolk Sac Tumor Arising in the Pancreas with Hepatic Metastasis: a Case Report

Primary Yolk Sac Tumor Arising in the Pancreas with Hepatic Metastasis: a Case Report

Difficulty in Diagnosing Peritoneal Fluid Cytology in Ovarian Yolk Sac Tumor Cases

Primary Yolk Sac Tumor of the Endometrium with MRI Findings: A Case Report

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