Zur Wirkung von Actinomycin C auf Acetabularia

The effects of actinomycin D and puromycin on morphogenesis in amphibian eggs and Acetabularia mediterranea

“…We therefore decided to study the effects of actinomycin D [which, since the work of Pierro (1961), is known to produce abnormalities in chick embryos] on morphogenesis in Acetabularia and amphibian embryos. A preliminary note (Brachet and Denis) was pubHshed early in 1963; our main conclusions have already been confirmed by Fhckinger (1963) and Wallace and Elsdale (1963) for amphibian eggs, and by Schweiger and Schweiger ( 1963 ) and Zetsche ( 1964 ) for Acetabularia.…”

The Circadian Rhythm in Photosynthesis in Acetabularia in the Presence of Actinomycin D, Puromycin, and Chloramphenicol

“…Eisenstadt and Brawerman (8) have shown that the incorporation of labeled amino acids into protein in isolated chloroplasts from Euglena is sensitive to puromycin, less so to actinomycin, and insensitive to chloramphenicol. In Acetabularia, actinomycin C and D (10-40 Mg mll) and puromycin (3-30 Mg mll) cause marked reduction in growth and cap formation (2,5,6,17,23). The morphology of the nucleus and chloroplasts appears to be modified by the presence of actinomycin D (10-20 ,g ml-') and puromycin (10 ug ml-) (1,3,6).…”

Actinomycin D‐induced Changes in Growth and Ribonucleic Acid Metabolism in the Gametophytes of Bracken Fern

“…A number of studies have related actinomycin D effects to an impairment of the transcription of DNA into RNA. Recent investigations using plant tissues have shown that synthesis of DNAdependent RNA, sensitive to actinomycin D treatment, is essential for auxin-induced growth in plants (Nooden and Thimann, 1963;Key and Shannon, 1964), morphogenesis in Acetabularia (Brachet and Denis, 1963;Schweiger and Schweiger, 1963;Brachet, Denis, and De Vitry, 1964;Zetsche, 1964), phytochrome-induced synthesis of anthocyanins (Lange and Mohr, 1965) and expansion of cotyledons (Mohr, Schlickewei, and Lange, 1965), and kinetin-induced bud formation in moss protonemata (Brandes and Bopp, 1965). Since actinomycin D markedly affects RNA in the nuclei-rich and ribosome-rich fractions of Pteridium gametophytes, its action fits that generally described in other systems.…”