PWI seems to be useful in the differential diagnosis of ring-enhancing cerebral lesions. High rCBV values in the peripheral areas appear to indicate the possibility of a necrotic tumour, whereas low values tend to indicate an abscess.
SUMMARY By analyzing time-activity curves over selected brain regions, following intravenous administration of a non-diffusible radionuclide, it is possible to assess regional arm-brain mean transit time (rABmtT).By evaluating this parameter in normal subjects a relatively small range of differences between symmetrical regions can be found (030 ± 0.14 sec, mean ± SD). An increase of this difference above statistical limits was found in 82 % of patients with acute complete stroke, in 56 % of patients with chronic complete stroke and in 21 % of patients with transient iscbemic attacks.Stroke, Vol 12, No 2, 1981
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