A monoclonal antibody to Dermatophagoides pteronyssinus is described that cross-reacts with an IgE-binding antigen present in insects, Crustacea (e.g. shrimp) and other invertebrates. By means of sodium dodecyl sulfate-polyacrylamide gel electrophoresis, gel filtration and immunofluorescence it was shown that this monoclonal antibody presumably recognizes tropomyosin. Tropomyosin was shown to be involved in cross-reactivity between mite, shrimp and insects in shrimp-allergic patients.
Selected food allergens have been measured in 11 house dust samples. The amount of ovomucoid ranged from 170 to 6,300 ng/g dust. The amount of β-lactoglobulin ranged from < 16 to 71 ng/g dust. Ovomucoid levels in some house dust samples are probably sufficiently high to cause sensitization and/or symptoms via inhalation.
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