Background: Polycystic ovarian syndrome (PCOS) is a neuroendocrine metabolic disorder characterized by an irregular menstrual cycle. Treatment for PCOS using synthetic drugs is effective. However, PCOS patients are attracted towards natural remedies due to the effective therapeutic outcomes with natural drugs and the limitations of allopathic medicines. In view of the significance of herbal remedies, herein, we discuss the role of different herbs in PCOS. Methods: By referring to the Scopus, PubMed, Google Scholar, Crossref and Hinari databases, a thorough literature search was conducted and data mining was performed pertaining to the effectiveness of herbal remedies against PCOS. Results: In this review, we discuss the significance of herbal remedies in the treatment of PCOS, and the chemical composition, mechanism of action and therapeutic application of selected herbal drugs against PCOS. Conclusions: The present review will be an excellent resource for researchers working on understanding the role of herbal medicine in PCOS.
Natural medicine plays a significant role in pharmaceutical industry. Phaseolus vulgaris L is a naturally available plant which is very frequently used in our daily life. Phaseolus vulgaris L is commonly known as bean; is an annual leguminous plant, belonging to family Fabaceae. Phaseolus vulgaris L is highly nutritious, easily and cheaply available. It is indigenous to central and South America. Phaseolus vulgaris L has wide number of uses due to its high content of phytochemical constituents. Flavonoids are responsible for its wide range of uses like antioxidant and neuroprotection. Phaseolus vulgaris L is most commonly taken by mouth for weight loss and obesity. It is also commonly taken for treatment of diabetes. The seed is diuretic, hypotensive and also used in the treatment of cancer of the blood. The present review reveals nutritional values, geographical conditions, propagation, collection and cultivation, phytochemical constituents and pharmacological activities of Phaseolus vulgaris L.
The present study was undertaken to explore the cardioprotective effect of Jatropha curcas fruit extracts against carbon tetrachloride induced cardiotoxicity in rats. Cardiotoxicity was induced by CCl4 (3ml/kg body weight) in animals. Blood biochemical, hematological parameters and histopathological studies were carried to assess the cardioprotective effect. CCl4 administration induced significant cardiotoxicity in rats, which was evident from enhanced levels of glucose, cholesterol, triglycerides and all hematological parameters. Pretreatment of silymarin (50mg/kg dose orally) significantly reversed carbon tetrachloride induced cardiotoxicity. From the obtained results it may be concluded that Jatropha curcas methanol extract (250mg/kg body weight) showed significant protective effect against CCl4 induced cardiotoxicity in rats than Jatropha curcas aqueous extract (p<0.001) for most of the blood biochemical parameters, hematological parameters as well in attenuation of pathological changes in heart tissues.
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