Ethanol extract of M. malabathricum leaf possesses significant antidiabetic and antihyperlipidaemic activity in diabetic rats.

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The aim of the study was to investigate the hepatoprotective activity of ethanol extract of whole plant of Canscora perfoliata in CCl4 induced hepatotoxic rats. Administration of hepatotoxins (CCl4) showed significant elevation of serum SGOT, SGPT, ALP, bilirubin, conjugated, unconjugated bilirubin and lipid peroxidation. Treatment with Canscora perfoliata (150 and 300mg/kg) significantly reduced the above mentioned parameters. The plant extract also enhanced the antioxidant activity. The ethanol extract of Canscora perfoliata have significant effect on the CCl4 induced hepatotoxicity animal models.

The antioxidant activity of Xanthosoma violaceum Schott corm extract was assayed through in vitro models such as DPPH, Hydroxyl, Superoxide and ABTS radical cation scavenging and reducing power. The total phenolics and flavonoids methanol extract were found to be 0.37g100-1 and 0.48g100-1 respectively. The methanol extract of Xanthosoma violaceum corm showed potent of in vitro antioxidant activities. The maximum inhibitory concentration (IC50) in all models viz Superoxide, ABTS, DPPH and Hydroxyl radical were found to be 73.84, 36.65, 24.56 and 21.04 µg/ml., respectively at 1mg/ml concentration. The finding of the present study confirmed the presence of total phenolics, flavonoids and possess in vitro antioxidant activity.