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SummaryIn our earlier paper, the intravenous injection of Zn O into rabbits, prepared by heating metallic zinc at 1 000 0 C, resulted in rising body temperature of rabbits It is our postulation that the semiconductor shows properties of an oxidative catalyst in the blood, suggesting that the inhalation of catalytically active metallic oxide fumes, a semiconductor, can cause metal fume fever Catalytically active metallic oxide fumes were produced by heating within the proper temperature range and their absorbing CO, forming the basic semiconductor, and their inhalation by rabbits resulted in metal fume fever.Rabbits were exposed to various kinds of metal fumes containing a trance of CO, which were heated at the proper temperature Changes in their body temperature and leucocyte count were observed Samples used Mg O, Zn, Zn O and Pb.The results are as follows:1 The fever development depends upon the effect of metal fumes absorbed CO rather than the metal fume concentration.2 N-type semiconductors such as Mg O, Zn O and Pb O having adsorbed CO, cumulative chemisorption, exhibit increased catalytical activation.3 In order to get properties as the semiconductor catalyst, it is necessary to heat metal fumes constantly at the activating temperature.4 The inhalation of only metal fumes does not cause fever development but does cause leucocytosis The fever development and the leucocytosis are clearly caused by inhalation of metal fumes having adsorbed CO and heated constantly within the correct temperature range Namely metal fume fever is caused by the inhalation of catalytically active metal fumes.

There have been many studies1,2,3,4,5,6) concerning the relation between size of arm cuff and blood pressure reading by cuff method, and several authorities e.g. WHO Expert Committee on Cardiovascular Diseases and Hypertension7), the American Heart Association8) and Cardiac Society of Great Britain and Irelands) have recommended various standards of cuff size. But yet neither the last word has been heard, nor the exact reasons for their choice have been given. In Japan, we have two different standards of cuff size: viz. Japanese Industrial Standard (JIS) and the Recommendation of Research Unit on Control of Hypertension and Cardiovascular Diseases by Grant of Japanese Ministry of Health and Welfare. But there is no experimental verification that any of these standards is adequate for the average Japanese adult. Moreover, as arm size has great influences upon the accuracy of the auscultatory blood pressure measurement 10) , it is worthwhile to study the relation between cuff size and blood pressure reading on Japanese adults who have generally smaller arms than Europeans and, if possible, to suggest a new adequate standard size of cuff for Japanese adults. The authors have measured the blood pressure of total 100 Japanese adults using various cuffs which have different sizes both in width and length, and have already published some part of the results in Japanese") elsewhere. In this present paper, results of all experiments on both male and female Japanese adults are summarized and statistically analyzed.

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