BackgroundShivering related to spinal anesthesia may interfere with monitoring and is uncomfortable. The aim of the present study was to investigate low-dose intrathecal meperidine for the prevention of shivering after induction of spinal anesthesia in parturients with cesarean section.MethodsThis was a prospective randomized, double-blind, placebo-controlled trial including 100 parturients, of American Society of Anesthesiologists (ASA) physical status I or II, scheduled for elective cesarean section under spinal anesthesia who were randomly assigned to a meperidine (0.2 mg/kg) plus hyperbaric lidocaine (5%, 75 mg, n = 50; group M) group or a placebo plus hyperbaric lidocaine (5%, 75 mg, n = 50; group L) group. Demographic and surgical data, adverse events, and the mean intensity for each parturient were assessed during the entire study period by a blinded observer.ResultsThere were no significant differences between the two study groups regarding the demographic and surgical data (P > 0.05). The incidence of shivering during the entire study period significantly decreased in the group of parturients who received intrathecal meperidine (P = 0.04). There were no significant differences in nausea and vomiting between the two groups.ConclusionsLow-dose intrathecal meperidine (10 mg) is safe and effective in reducing the incidence and severity of shivering associated with spinal anesthesia in parturients with cesarean section.
During general anesthesia a large number of surgeries such as pilonidal sinus excision are conducted in prone position. The main purpose of this research is the application of laryngeal mask airway in prone position in pilonidal cyst excision after Atracurium injection. A doubleblind descriptive experiment was performed on 85 patients (ASA I-II), such that they reclined on the operating table in prone position. After preoxygenation, general anesthesia was induced by Midazolam, Fentanyl, Propofol, and Atracurium. At the same position, the laryngeal mask airway was placed. Heart rate, systolic and diastolic blood pressure was reduced significantly after anesthesia. Laryngeal mask airway insertion was successful in 78 patients on first try. Induction/incision time was reduced. Laryngospasm and pulmonary aspiration was not observed and rate of sore throat was 16/85 patients. Based on our data, it seems that for minor surgeries in prone position, laryngeal mask airway is applicable after the administration of muscle relaxant, although further studies are required.
Introduction: Oesophageal squamous-cell carcinoma (SCC) is associated with lifestyle-related behaviours (i.e. malnutrition, alcohol and tobacco), which also increase the risk of perioperative complications (1,2). Previously the impact of complications on survival has been explored in mixed SCC and adenocarcinoma populations with conflicting results. In the present study, the influence of perioperative complications on survival following open oesophageal resection was investigated exclusively in patients with SCC.
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