Numerous laboratory parameters were examined in 235 patients with generalized psoriasis treated orally with retinoid and in 35 patients treated topically with anthralin as control. Computer evaluation of the obtained data revealed statistical trends to elevation of the total serum bilirubin level and increasing number of blood monocytes after long-term oral treatment. No other statistically significant changes of the laboratory data were found. Particularly, the liver function tests (transaminases, prothrombin and alkaline phosphatase) showed no significant alterations. Only in a few cases did the retinoid compound have an influence on the GPT and GOT levels. The reasons for this individual sensitivity to the drug remain unknown. No significant alterations were found in the control group treated topically with anthralin.

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The cases of Dermatofibrosis lenticularis disseminata (DLD) published under this name are specified in tabular form. It appears that only 11 of the 21 cases can be coordinated to the Buschke-Ollendorff-syndrome – namely those with DLD and O. After explaining an own observation the cases hitherto published are discussed, and the pros and cons of their classification in the syndrome are treated. – Special attention is called to the participation of the elastic tissue to the DLD as proved by us.

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