In many higher education institutions of Ukraine there are centers of distance education, the system of which is based on a number of principles: continuity; democratization; integration; globalization. In the conditions of the declared quarantine connected with the Covid–19 pandemic in the educational process of higher educational institutions and medical in particular distance learning has become especially relevant. The aim is to descriptive the forms and methods of distance learning on the example of microbiology, virology and immunology in TNMU and department of microbiology, virology and immunology ZSMU. Microsoft Office 365 (MS Teams application) and Skype for Business were chosen as the main platforms for the implementation of distance learning at ZSMU for the quarantine period. As a platform for distance education at the Department of Microbiology, Virology and Immunology, TNMU used the capabilities of Moodle. Distance learning at ZSMU and TNMU was carried out according to the schedule drawn up at the beginning of the semester using two forms of education, because this combination best helps to implement and ensure the learning process: online conferences and coverage of all materials on the department’s website. The advantages of distance learning are obvious today.This form of learning has significant potential, because the software capabilities of the Microsoft Office 365 and Moodle platforms allow you to quickly transfer any amount of study material to students with its subsequent storage and permanent access for self-study and repetition, as well as various forms of student knowledge control and documentation of the received marks. For successful distance learning it is very important to choose the optimal form of learning or a combination thereof. However, it cannot completely replace traditional education and necessarily requires practical work, especially when studying disciplines at the Department of Microbiology, Virology and Immunology.